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Effects of a gestational weight gain restriction program for obese women : Sibling pairs’ weight development during the first five years of life

Objectives: Successful gestational weight gain (GWG) restriction programs for obese (Body Mass Index (BMI) ≥ 30 kg/m2) pregnant women, have not, so far, shown convincing effects on infant's weight development. An intervention starting during the pregnancy might be too late and a pre-conceptional life style change may be preferable. Thus, the aim of this study was to follow children born to mothers

Factorizations induced by complete Nevanlinna–Pick factors

We prove a factorization theorem for reproducing kernel Hilbert spaces whose kernel has a normalized complete Nevanlinna–Pick factor. This result relates the functions in the original space to pointwise multipliers determined by the Nevanlinna–Pick kernel and has a number of interesting applications. For example, for a large class of spaces including Dirichlet and Drury–Arveson spaces, we construc

Republika Srpska : Imaginary, performance and spatialization

Conceptually, this paper is about the becoming of states and how such states are a socially constructed spaces, imagined and performed by those who perceive themselves as belonging to that state. It asks through what imaginaries and performative practices does a state come into being? More specifically, the paper investigates how the state is imagined and performed in times of war and peace hoping

Towards precision medicine in severe asthma : Treatment algorithms based on treatable traits

Asthma is a common disease, and although its clinical manifestations may be similar among patients, recent research discoveries have shown that it consists of several distinct clinical clusters or phenotypes, each with different underlying molecular pathways yielding different treatment responses. Based on these observations, an alternative approach - known as ‘precision medicine’ - has been propo

Radiological assessment of local resectability status in patients with pancreatic cancer : Interreader agreement and reader performance in two different classification systems

Objectives: To assess the interreader agreement and reader performance in the evaluation of patients with pancreatic cancer (PC) in two classification systems of local resectability status prior to initiation of therapy, namely the National Comprehensive Cancer Network (NCCN) and Karolinska classification system (KCS). Methods: In this ethics review board-approved retrospective study, six radiolog

“I Refuse to Sink” : Narratives of the Dispossessed Within Refugee Stories on the Balkan Route

With the arrival of the refugees from the Middle East, especially since 2015, Europe has become a xenophobic hotbed. Discourses, practices, and policies promoting and supporting xenophobia have become reality. In this article, we seek to present stories of those who have arrived to Europea via the Balkan Route, in a qualitative research fashion, concentrating on several narratives collected by the

Short article : Influence of regulatory NLRC5 variants on colorectal cancer survival and 5-fluorouracil-based chemotherapy

Background NLRC5 is an interferon γ-inducible protein, which plays a role in immune surveillance with a potential influence on cancer survival. Objective We aimed to evaluate the effect of potential regulatory variants in NLRC5 on overall survival and survival after 5-fluorouracil (5-FU)-based therapy of colorectal cancer (CRC) patients. Patients and methods We carried out a case-only study in a C

Fetal rotation during vacuum extractions for prolonged labor : a prospective cohort study

Introduction: The aim of the study was to investigate fetal head rotation during vacuum extraction. Material and methods: We conducted a prospective cohort study from November 2013 to July 2016 in seven European hospitals. Fetal head position was determined with transabdominal or transperineal ultrasound and categorized as occiput anterior (OA), occiput transverse (OT) or occiput posterior (OP) po

Conspecific boldness and predator species determine predation-risk consequences of prey personality

Abstract: Individual variation in the behavior of prey can influence predation risk in complex ways. We ran individual roach (Rutilus rutilus), a common freshwater fish, through a standard refuge emergence protocol to characterize their boldness, a key animal personality trait. We then paired a bold and a shy roach and exposed the pair to one of two predator species that have contrasting hunting m

Access to the Bis-benzene Cobalt(I) Sandwich Cation and its Derivatives : Synthons for a “Naked” Cobalt(I) Source?

The synthesis and structural characterization of the hitherto unknown parent Co(bz)2 + (bz=benzene) complex and several of its derivatives are described. Their synthesis starts either from a CoCO5 + salt, or directly from Co2(CO)8 and a Ag+ salt. Stability and solubility of these complexes was achieved by using the weakly coordinating anions (WCAs) [Al(ORF)4]− and [F{Al(ORF)3}2]− {RF=C(CF3)3} and

Models of care for survivors of childhood cancer from across the globe : Advancing survivorship care in the next decade

With improvements in cancer treatment and supportive care, a growing population of survivors of childhood cancer at risk for significant and potentially life-threatening late effects has been identified. To provide a current snapshot of the models of care from countries with varying levels of resources and health care systems, stakeholders in childhood cancer survivorship clinical care and researc

Validation of the Rowland Universal Dementia Assessment Scale (RUDAS) in a multicultural sample across five Western European countries : diagnostic accuracy and normative data

Background:: With increasing cultural diversity and growing elderly immigrant populations in Western European countries, the availability of brief cognitive screening instruments adequate for assessment of dementia in people from diverse backgrounds becomes increasingly important. The aim of the present study was to investigate diagnostic accuracy of the Rowland Universal Dementia Assessment Scale

The role of parent and offspring sex on risk for externalizing psychopathology in offspring with parental alcohol use disorder : a national Swedish study

Purpose: The substantial literature showing that offspring of parents with alcohol use disorder (AUD) is at increased risk for externalizing psychopathology rarely examines the differential effects of parental and offspring sex. This literature also has other important limitations, such as modest sample sizes and use of unrepresentative samples. Using a large, nationwide Swedish sample, we aim to

Dose-response effects of omega-3 on platelet aggregation: an observational study

ObjectiveThis study aimed to evaluate the dose-response effects of supplemental omega-3 fatty acids on platelet function in healthy volunteers.MethodsTwelve healthy volunteers ingested a normal supplemental dose of 1260 mg omega-3 fatty acids daily for 5 days, followed by a high dose of 2520 mg daily for another 5 days. Multiple electrode aggregometry (MEA) with four different agonists was used to