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Search for squarks and gluinos in events with isolated leptons, jets and missing transverse momentum at root s=8 TeV with the ATLAS detector

The results of a search for supersymmetry in final states containing at least one isolated lepton (electron or muon), jets and large missing transverse momentum with the ATLAS detector at the Large Hadron Collider are reported. The search is based on proton-proton collision data at a centre-of-mass energy root s = 8 TeV collected in 2012, corresponding to an integrated luminosity of 20 fb(-1). No

Simultaneous quantification of myocardial perfusion, oxidative metabolism, cardiac efficiency and pump function at rest and during supine bicycle exercise using 1-11C-acetate PET - a pilot study

P>Background: PET using 1-11C-acetate (ACE-PET) applied at rest is used for measuring absolute myocardial blood flow (MBF) and oxidative metabolic rate (k(mono)). We evaluated the feasibility of quantitative ACE-PET during exercise. Methods: Five endurance athletes underwent dynamic PET scanning at rest and during supine bicycle stress. Exercise was maintained at a workload of 120 Watt for 17 min.

Light in and sound out: emerging translational strategies for photoacoustic imaging.

Photoacoustic imaging (PAI) has the potential for real-time molecular imaging at high resolution and deep inside the tissue, using nonionizing radiation and not necessarily depending on exogenous imaging agents, making this technique very promising for a range of clinical applications. The fact that PAI systems can be made portable and compatible with existing imaging technologies favors clinical

Efficient modeling of sun/shade canopy radiation dynamics explicitly accounting for scattering

Abstract in UndeterminedThe separation of global radiation (Rg) into its direct (Rb) and diffuse constituents (Rg) is important when modeling plant photosynthesis because a high Rd:Rg ratio has been shown to enhance Gross Primary Production (GPP). To include this effect in vegetation models, the plant canopy must be separated into sunlit and shaded leaves. However, because such models are often to

A Critical Mapping of Practice-Based Research as Evidenced by Swedish Architectural Theses

This article presents an investigation that was funded by the Swedish Institute into the role of creative practice in architectural research as evidenced in Swedish doctoral theses. The sample was mapped and analysed in terms of clusters of interest, approaches, cultures of knowledge and uses of creative practice. This allowed the identification of the ontological, epistemological and methodologic

Mesenchymal stromal cells from primary osteosarcoma are non-malignant and strikingly similar to their bone marrow counterparts.

Mesenchymal stromal cells (MSC) are multipotent cells that can be isolated from a number of human tissues. In cancer, MSC have been implicated with tumor growth, invasion, metastasis, drug resistance and were even suggested as possible tumor-initiating cells in osteosarcoma (OS). However, MSC from OS and their possible tumor origin have not yet been thoroughly investigated. Therefore, primary OS m

Conodont biostratigraphy, and delta C-13 and delta S-34 isotope chemostratigraphy, of the uppermost Ordovician and Lower Silurian at Osmundsberget, Dalarna, Sweden

The previously established graptolite and chitinozoan Hirnanian-Telychian biostratigraphy in the unique Osmundsberget North outcrop in the Siljan region, south-central Sweden, is integrated with new conodont biostratigraphy and C-13(org), C-13(carb) and S-34(pyr) chemostratigraphy. At this locality, the middle Hirnantian (latest Ordovician) topmost part of the Boda Limestone is overlain by the lat

Flap Dynamics in Aspartic Proteases : A Computational Perspective

Recent advances in biochemistry and drug design have placed proteases as one of the critical target groups for developing novel small-molecule inhibitors. Among all proteases, aspartic proteases have gained significant attention due to their role in HIV/AIDS, malaria, Alzheimer's disease, etc. The binding cleft is covered by one or two β-hairpins (flaps) which need to be opened before a ligand can

Ultrafast photoinduced dynamics in quantum dot-based systems for light harvesting

Colloidal semiconductor nanocrystals, referred to as quantum dots, offer simple low-temperature solution-based methods for constructing optoelectronic devices such as light emitting diodes and solar cells. We review recent progress in the understanding of photoinduced processes in key components of a certain type of quantum dot solar cells where the dots sensitize a suitable metal oxide, such as Z

Gastrointestinal dysfunction in liver cirrhosis.

Patients with liver cirrhosis exhibit several features of gut dysfunction which may contribute to the development of cirrhosis complications as well as have an impact on nutritional status and health-related quality of life. Gastrointestinal symptoms are common in cirrhosis and their pathophysiology probably involves factors related to liver disease severity, psychological distress, and gut dysfun

Bumble bees show trait-dependent vulnerability to landscape simplification

Agricultural intensification has resulted in large-scale loss of bee pollinators, but while some species have been negatively affected others seem to endure changed conditions. It has been suggested that certain morphological, ecological and life-history traits make some species more vulnerable to landscape changes. Information on which traits make species vulnerable and why may aid conservation o

A Novel System for Source Characterization and Controlled Human Exposure to Nanoparticle Aggregates Generated During Gas–Metal Arc Welding

Abstract in Undetermined The aim of this study was to achieve a method to perform detailed characterization and human exposure studies of nanosized and nanostructured aerosol particles. The source chosen was mild steel, active gas, arc welding fume. The setup consisted of a generation chamber, where welding can be performed, connected to an airtight stainless steel 22 m(3) exposure chamber. Instru

Search for excited leptons in proton-proton collisions at root s=7 TeV with the ATLAS detector

The ATLAS detector is used to search for excited leptons in the electromagnetic radiative decay channel l* -> l gamma. Results are presented based on the analysis of pp collisions at a center-of-mass energy of 7 TeV corresponding to an integrated luminosity of 2.05 fb(-1). No evidence for excited leptons is found, and limits are set on the compositeness scale Lambda as a function of the excited le

Messages from the morgue to rheumatology: from Chagas disease to giant cell arteritis.

Autopsy rates have fallen from over 50% to less than 10% in recent decades. The drastic decline creates uncertainty regarding causes of death and has negative effects for research, training, and patient safety, despite advances in imaging and laboratory testing. Rheumatology is as much at a loss as other specialties. Examples are given of important missed diagnoses revealed only at autopsy.