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Identification of Asthma Phenotypes in the Spanish MEGA Cohort Study Using Cluster Analysis

Introduction: The definition of asthma phenotypes has not been fully established, neither there are cluster studies showing homogeneous results to solidly establish clear phenotypes. The purpose of this study was to develop a classification algorithm based on unsupervised cluster analysis, identifying clusters that represent clinically relevant asthma phenotypes that may share asthma-related outco

Obesity and the risk of cardiometabolic diseases

The prevalence of obesity has reached pandemic proportions, and now approximately 25% of adults in Westernized countries have obesity. Recognized as a major health concern, obesity is associated with multiple comorbidities, particularly cardiometabolic disorders. In this Review, we present obesity as an evolutionarily novel condition, summarize the epidemiological evidence on its detrimental cardi

Ecology, Agents, and the Causes of Selection : A Reply to Shuker

Shuker points to some inconsistencies in my terminology about consequence laws in evolutionary biology, specifically that gene flow and recombination are not as easily classified as one gets the impression of after reading Sober (1984). I agree, and I also emphasize that evolutionary biology should not only focus on consequence laws, but also source laws arising from the ecological selective envir

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This paper analysis sexual scripts theory in relation to gay men courtship, love relationships, and casual sex. The aim is to understand how gay masculinity is evolving in the 21st Century. Previous research has reinforced the concept that gay men follow heterosexual masculinity and scripts in their relationships with other men. Here, analysing data from the most used gay dating app ‘Grindr’, we t