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Streptococcal M1 protein induces hyporesponsiveness and cytokine release from human arteries in a fibrinogen-dependent manner : A translational study

Background: Streptococcus pyogenes is a Gram positive bacterial species commonly involved in sepsis. Invasive strains express virulence factors such as the M1 protein. M1 protein forms complexes with fibrinogen leading to a cytokine storm in plasma contributing to the development of septic shock and organ failure. In experimental animals M1 protein causes vascular nitric oxide production and hypor

First Polarimetric Investigation of Malaria Mosquitos as Lidar Targets

In this work, we use a novel spectral polarimetric optical tomographic imaging goniometer (SPOTIG) to investigate the scattering properties of Anopheles malaria mosquitoes to aid in their detection and identification in entomological lidar applications. Mosquitoes were mounted on a turn table, on which they were illuminated from different angles with linearly polarized near infrared light and rota

Compton scattering from the deuteron above pion-production threshold

The electromagnetic polarizabilities of the nucleon are fundamental nucleon-structure observables that characterize its response to external electromagnetic fields. The neutron polarizabilities can be accessed from Compton-scattering data on light nuclear targets. Recent measurements of the differential cross section for Compton scattering on the deuteron below the pion-production threshold have d

Sustainable synthesis and characterization of a bisphenol A-free polycarbonate from a six-membered dicyclic carbonate

A bisphenol A (2,2-bis(4-hydroxyphenyl)propane, BPA)-free polycarbonate (PC) from a six-membered di-cyclic carbonate, di-trimethylolpropane di-cyclic carbonate (DTMPC), was developed as a new type of PC by ring opening homo-polymerization. The polymerization was controlled by using metal-free organic-based catalyst systems. The results indicated that the conversion rate depends on the basicity of

Targeted prevention in primary care aimed at lifestyle-related diseases : A study protocol for a non-randomised pilot study

Background: The consequences of lifestyle-related disease represent a major burden for the individual as well as for society at large. Individual preventive health checks to the general population have been suggested as a mean to reduce the burden of lifestyle-related diseases, though with mixed evidence on effectiveness. Several systematic reviews, on the other hand, suggest that health checks ta

Normal and resonant Auger spectroscopy of isocyanic acid, HNCO

In this paper, we investigate HNCO by resonant and nonresonant Auger electron spectroscopy at the K-edges of carbon, nitrogen, and oxygen, employing soft X-ray synchrotron radiation. In comparison with the isosteric but linear CO2 molecule, spectra of the bent HNCO molecule are similar but more complex due to its reduced symmetry, wherein the degeneracy of the π-orbitals is lifted. Resonant Auger

Sex-based differences in association between circulating T cell subsets and disease activity in untreated early rheumatoid arthritis patients

Background: It is not known if sex-based disparities in immunological factors contribute to the disease process in rheumatoid arthritis (RA). Hence, we examined whether circulating T cell subset proportions and their association with disease activity differed in male and female patients with untreated early rheumatoid arthritis (ueRA). Methods: Proportions of T cell subsets were analyzed in periph

Hen. Bakgrund, attityder och användande

År 2015 infördes det könsneutrala pronomenet hen i Svenska akademins ordlista efter en känslomässig allmän debatt om ordet, dess innebörd och möjliga konsekvenser. Hösten 2015 genomförde vi en större enkätundersökning som besvarades av 1308 personer registrerade i Enkätfabrikens deltagarpanel. Enkäten presenterades som en studie om attityder i aktuella frågor, till exempel attityder till jämställd

Experimental Evaluation of the Performance of CoMP Systems for Closely-Located Users Including Users' Body Influence

Based on multi-link synchronous propagation measurements, we study the downlink performance of Coordinated Multi-point (CoMP) systems. The propagation measurements took place in an outdoor micro-cellular environment with two base stations (BSs) located 60 m apart, each equipped with two cross-polarized co-located antennas. We focus on the challenging case of having closely-located users with 0.5 m

Varför idrottare dopar sig : En intervjustudie om vad som underbygger dopingbruk hos svenska idrottare

I denna studie har elva svenska idrottare som dopat sig intervjuats – tio styrkelyftare och en tyngdlyftare. Idrottarna har varit verksamma på tävlings- till elitnivå, och har fällts för minst en dopingförseelse 1990 till och med 2006. Syftet med studien har varit att identifiera och analysera sociala processer som ligger bakom bruket. Anabola Androgena Steroider (AAS) var det preparat som samtlig

On the Nature of the Countermovement: A Response to Stuart et al.’s ‘Climate Change and the Polanyian Countermovement: Carbon Markets or Degrowth?’

In a recent article for this journal, Stuart, D., Gunderson, R., and Petersen, B. [(2017). Climate change and the Polanyian counter-movement: carbon markets or degrowth? New political economy, 1–14. doi:10.1080/13563467.2017.1417364] discuss solutions to climate change in terms of Karl Polanyi’s concept of the double movement. They set up their argument as a critique of my own article on the topic

Mechanics of a mosquito bite with applications to microneedle design

The mechanics of a fascicle insertion into the skin by a mosquito of the type aedes aegypti has been studied experimentally using high-speed video (HSV) imaging, and analytically using a mathematical model. The fascicle is a polymeric microneedle composed of a ductile material, chitin. It has been proposed that the mosquito applies a non-conservative follower force component in addition to the Eul

Relative survival in patients with dementia with Lewy bodies and Parkinson’s disease dementia

IntroductionThe understanding of survival in dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD) is limited, as well as the impact of these diagnoses in an ageing co-morbid population.MethodsA retrospective study of 177 patients who received a DLB or PDD diagnosis between 1997–2014 at the Memory Clinic in Malmö, Sweden. Relative survival was evaluated by adjusting all-cause surv

Living with Lewy body dementia. Treatment, survival & quality of life.

Background: Patients with Lewy body dementias (LBD) have a complex clinical picture. With no prevention or cure, management focuses around symptomatic relief, however pharmacological and non-pharmacological options have been inadequately investigated. Moreover, the understanding of survival, prognostic factors and impact of the diagnosis in an already ageing and comorbid population is limited. Eve

Safety of the Deferral of Coronary Revascularization on the Basis of Instantaneous Wave-Free Ratio and Fractional Flow Reserve Measurements in Stable Coronary Artery Disease and Acute Coronary Syndromes

Objectives: The aim of this study was to investigate the clinical outcomes of patients deferred from coronary revascularization on the basis of instantaneous wave-free ratio (iFR) or fractional flow reserve (FFR) measurements in stable angina pectoris (SAP) and acute coronary syndromes (ACS). Background: Assessment of coronary stenosis severity with pressure guidewires is recommended to determine