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The contact system-a novel branch of innate immunity generating antibacterial peptides.

Activation of the contact system has two classical consequences: initiation of the intrinsic pathway of coagulation, and cleavage of high molecular weight kininogen (HK) leading to the release of bradykinin, a potent proinflammatory peptide. In human plasma, activation of the contact system at the surface of significant bacterial pathogens was found to result in further HK processing and bacterial

MAX-IV lattice, dynamic properties and magnet system

At MAX-LAB the next synchrotron light source MAX-IV is currently studied (Proceedings of the seventh European Particle Accelerator Conference, EPAC 02, Paris, France, 2002). In this paper, we present a possible lattice with horizontal emittance of 1.2 nm rad at an energy of 3 GeV. The possibilities to realise the main magnetic system with high gradient integrated magnets are studied with 2D and 3D

Boundary behavior in Hilbert spaces of vector-valued analytic functions

In this paper we study the boundary behavior of functions in Hilbert spaces of vector-valued analytic functions on the unit disc D. More specifically, we give operator-theoretic conditions on M-z, where M-z, denotes the operator of multiplication by the identity function on ID, that imply that all functions in the space have non-tangential limits a.e., at least on some subset of the boundary. The

Obesity and cardiovascular disease. Aspects of methods and susceptibility.

Popular Abstract in Swedish Fetma räknas som ett av världens tio viktigaste hälsoproblem enligt WHO och ökar i snabb takt. Man beräknar att över 1 miljard av världens vuxna befolkning är överviktig, d.v.s. har ett kroppsmasseindex (BMI) ?25.0 kg/m², varav 300 miljoner är feta, d.v.s. har ett BMI ?30.0 kg/m². I Sverige är 38% av kvinnor och 58% av män mellan 25 och 64 år överviktiga, och 11% respekThe aim of this thesis was to study the morbidity and mortality of cardiovascular disease (CVD) in obese individuals, as measured by different obesity measurements, and to explore how the CVD risk related to obesity was modified by other biologic and socio-demographic circumstances. Data from two population-based cohort studies was used. The Malmö Preventive Project included 22 444 middle-aged me

Recovery of recombinant cutinase using detergent foam

Foam generated by vigorous stirring of a nonionic detergent, Triton X-114, was used for the recovery of recombinant cutinase expressed by Saccharomyces cerevisiae. The enzyme with a hydrophobic fusion tag, (Trp-Pro)(4), was recovered with a higher yield as compared to the wild-type cutinase, indicating the involvement of hydrophobic interactions in protein isolation with the foam. The influence of

Adaptive enhancement and noise reduction in very low light-level video

A general methodology for noise reduction and contrast enhancement in very noisy image data with low dynamic range is presented. Video footage recorded in very dim light is especially targeted. Smoothing kernels that automatically adapt to the local spatio-temporal intensity structure in the image sequences are constructed in order to preserve and enhance fine spatial detail and prevent motion blu

A Case Study Investigating the Characteristics of Verification and Validation Activities in the Software Development Process

System verification and validation are important activitiesin the software development process aiming at testing thesoftware system in various quality aspects.The purpose of this study is to investigate theimportant characteristics of the verification andvalidation activities in the software development processin an organization. A qualitative research method isemployed in order to facilitate the

Full oscillation cycle phase noise analysis of differential CMOS LC oscillators

This paper analyzes the phase noise of the widely used differential LC oscillator topology and presents brief equations describing phase noise over the entire oscillation period. The findings show that if a capacitance is present at the source node of the differential pair, two phenomena occur that increase the phase noise: the switch time increases, lengthening the interval spent in a noisy balan

Managerial type as related to percept-genetic signs of anxiety and defense in the Defense Mechanism Technique modified (DMTm)

The study considers relations in a group of 95 managers, 41 women and 54 men, between managerial type and signs of anxiety and defense in the Defense Mechanism Technique modified (DMTm). Eight managerial types were distinguished, based on ratings of the managers by their subordinates in terms of the Ekvall and Arvonen (1991) leadership style dimensions of employee-centeredness, change-centeredness

Deconvolution under monotonicity assumptions

We state limit distribution results for the isotonic inverse estimator of a distribution function when the data are disturbed by a random variable with a decreasing density. Three different dependence structures are considered: independent, weak dependent and suboordinated gaussian long range dependent data.

Craniofacial dysmorphology in Swedish schizophrenia patients

Objective: To perform detailed assessments of craniofacial dysmorphology in individuals with schizophrenia and controls in Sweden, in order to further elucidate the neurodevelopmental origins of schizophrenia. Method: We performed detailed, anthropometric assessments of craniofacial dysmorphology in male patients with schizophrenia (n = 24), healthy controls (n = 16), and patients' siblings with s

Proteoglycan production in disomic and trisomy 7-carrying human synovial cells.

To gain further insight into the synthesis and structure of the synovial matrix of joints, we have established cell cultures from synovial specimens and elaborated their production of hyaluronan and proteoglycans. The cultures secreted mainly the small proteoglycan decorin, but also considerable amounts of the related biglycan and the large proteoglycan versican. Only minor amounts of heparan sulf