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Knowledge, attitudes, beliefs, and stigma related to latent tuberculosis infection : a qualitative study among Eritreans in the Netherlands

BACKGROUND: Tailored and culturally appropriate latent tuberculosis (TB) infection screening and treatment programs, including interventions against TB stigma, are needed to reduce TB incidence in low TB incidence countries. However, we lack insights in stigma related to latent TB infection (LTBI) among target groups, such as asylum seekers and refugees. We therefore studied knowledge, attitudes,

Factors Determining Treatment Success in Children with Drug-Sensitive Tuberculosis in Ethiopia : A Three-Year Retrospective Analysis

This study in the Amhara and Oromia regions of Ethiopia assessed the outcomes of tuberculosis (TB) treatment among children younger than 15 years. Retrospective data were collected on treatment outcomes and their determinants for children with TB for the cohorts of 2012-2014 enrolled in 40 hospitals and 137 health centers. Chi-square tests, t-tests, and logistic regression were used for the analys

Use of Xpert Contributes to Accurate Diagnosis, Timely Initiation, and Rational Use of Anti-TB Treatment Among Childhood Tuberculosis Cases in South Central Ethiopia

Background: Childhood tuberculosis (TB) was under-prioritized, and only 15% of childhood TB cases are microbiologically confirmed. Hence, most childhood TB diagnoses are made on a clinical basis and prone to over- or under-treatment. Xpert is a rapid method for the diagnosis of childhood TB with high sensitivity.Objective: To assess the use of Xpert for accurate diagnosis, timely initiation, and r

Predictors of Virologic Failure Among a Cohort of HIV-infected Children in Southern Ethiopia

BACKGROUND: Optimal care for children with HIV infection includes timely assessment of treatment failure. Using HIV viral load to define treatment failure remains a challenge in resource-limited settings.METHODS: Children with HIV infection who were already on or starting first-line antiretroviral therapy were enrolled and followed over time. We examined clinical and immunologic predictors of viro

Patient and health system delay among TB patients in Ethiopia : Nationwide mixed method cross-sectional study

BACKGROUND: Effective tuberculosis (TB) control is the end result of improved health seeking by the community and timely provision of quality TB services by the health system. Rapid expansion of health services to the peripheries has improved access to the community. However, high cost of seeking care, stigma related TB, low index of suspicion by health care workers and lack of patient centered ca

High urban tuberculosis case notification rates can be misleading : evidence from an urban setting in Ethiopia

BACKGROUND: Tuberculosis (TB) is a major public health problem. Its magnitude the required interventions are affected by changes in socioeconomic condition and urbanization. Ethiopia is among the thirty high burden countries with increasing effort to end TB. We aimed to describe the case notification rate (CNR) for urban tuberculosis (TB) and estimate the percentage of TB patients who are not from

Stigma matters in ending tuberculosis : Nationwide survey of stigma in Ethiopia

BACKGROUND: Tuberculosis (TB) affects, and claims the lives of, millions every year. Despite efforts to find and treat TB, about four million cases were missed globally in 2017. Barriers to accessing health care, inadequate health-seeking behavior of the community, poor socioeconomic conditions, and stigma are major determinants of this gap. Unfortunately, TB-related stigma remains unexplored in E

Knowledge, attitudes, and practices related to TB among the general population of Ethiopia : Findings from a national cross-sectional survey

INTRODUCTION: Ethiopia is among the high-burden countries for tuberculosis (TB), TB/HIV, and drug-resistant TB. The aim of this nationwide study was to better understand TB-related knowledge, attitudes, and practices (KAPs) and generate evidence for policy and decision-making.MATERIALS AND METHODS: We conducted a cross-sectional TB KAP survey in seven regions and two city administrations of Ethiop

Incidence of tuberculosis and early mortality in a large cohort of HIV infected patients receiving antiretroviral therapy in a tertiary hospital in Addis Ababa, Ethiopia

Preceding studies on morbidities and mortalities associated with TB in a cohort of HIV care indicate high incidence of TB development and premature death among patients on highly active antiretroviral treatment (HAART). This study aims to measure the rate of TB, TB mortality, and associated risk factors following commencement of HAART in a cohort of patients attending HIV care in Ethiopia. Patient

The role of private health facilities in the provision of malaria case management and prevention services in four zones of Oromia Regional State, Ethiopia

Little is known about the contribution of the private health sector in managing malaria cases and contributing to malaria prevention and control efforts in Ethiopia. We assessed 102 private health facilities and 92 drug outlets in 20 districts of Oromia Regional State, Ethiopia, for their provision of malaria-specific services. Of the assessed health facilities 86% provided such services. Diagnosi

Evaluation of collaborative TB/HIV activities in a general hospital in Addis Ababa, Ethiopia

BACKGROUND: Ethiopia has had mechanisms for TB/HIV collaborative activities since 2002. However, no published account has defined the role of these collaborative efforts in strengthening linkages between HIV and TB management units at the point-of-care level. Our objective was to assess the extent of linkages between the two programs at the patient management level at Zewditu Memorial Hospital in