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Longitudinal Flow Decorrelations in Xe+Xe Collisions at sNN =5.44 TeV with the ATLAS Detector

The first measurement of longitudinal decorrelations of harmonic flow amplitudes vn for n=2-4 in Xe+Xe collisions at sNN=5.44 TeV is obtained using 3 μb-1 of data with the ATLAS detector at the LHC. The decorrelation signal for v3 and v4 is found to be nearly independent of collision centrality and transverse momentum (pT) requirements on final-state particles, but for v2 a strong centrality and p

Towards Precise Localisation : Subsample Methods, Efficient Estimation and Merging of Maps

Over the last couple of years audio and radio sensors have become cheaper and more common in our everyday life. Such sensors can be used to form a network, from which one can obtain distance measures by correlating the different received signals. One example of such distance measures is time-difference of arrival measurements (TDoA), which can be used to estimate the positions of the senders and r

Longitudinal and azimuthal evolution of two-particle transverse momentum correlations in Pb-Pb collisions at √sNN= 2.76 TeV

This paper presents the first measurements of the charge independent (CI) and charge dependent (CD) two-particle transverse momentum correlators G2CI and G2CD in Pb–Pb collisions at √SNN=2.76 TeV by the ALICE collaboration. The two-particle transverse momentum correlator G2 was introduced as a measure of the momentum current transfer between neighboring system cells. The correlators are measure

Preventable fractions of cancer incidence attributable to 7-years weight gain in the Norwegian Women and Cancer (NOWAC) study

There is a lack of tangible measures for directed public health action to halt the increase in weight and cancer. We estimated the fraction and preventable cases of all and major body fatness-related cancers attributable to 7-years weight gain (≥ 2 kg). We assessed validated self-reported anthropometrics from 44,114 women aged 34–49 years at the enrolment in 1991–1992 and from a second questionnai

Paliperidone palmitate-induced facial angioedema : A case report

BACKGROUND: Paliperidone palmitate is a once-monthly injectable, atypical antipsychotic. To our knowledge, there has been only one report of paliperidone palmitate-induced angioedema presenting with acute laryngeal edema with subsequent respiratory arrest. Here, we present a case report of paliperidone palmitate-induced angioedema with a relatively mild clinical presentation compared with the prev

Preparation of cultured human vascular cells

Cerebral amyloid angiopathy (CAA) results from amyloid accumulation within arteries of the cerebral cortex and leptomeninges. This condition is age-related, especially prevalent in Alzheimer's disease (AD), and the main feature of certain hereditary disorders (i.e., HCHWA-I). The vascular smooth muscle cells (VSMCs) appear to play a vital role in the development of CAA, which makes them well suite

The Vbeta13 T Cell Receptor Monoclonal Antibody Reduces Hyaluronan and CD68+, CD3+, and CD8+ Cell Infiltrations to Delay Diabetes in Congenic BB DRLyp/Lyp Rats

The depleting Vβ13a T cell receptor monoclonal antibody (mAb) 17D5 prevents both induced and spontaneous autoimmune diabetes in BB rats. Here it was tested in congenic DRLyp/Lyp rats, all of which spontaneously developed diabetes. Starting at 40 days of age, rats were injected once weekly with either saline, His42 Vβ16 mAb, or 17D5 mAb and monitored for hyperglycemia. Diabetes occurred in 100% (n

Disease, Death, and Displacement : The long-term effects of early-life conditions on income, education, and health in Sweden, 1937-2011

How are people’s lives shaped by what they experience during infancy, childhood, and adolescence? How are their adult lives impacted by a sudden improvement or worsening in their early-life conditions?This dissertation aims at providing some insights about how specific changes in early-life conditions can affect individuals’ lives in the long-term. It focuses on three very different shocks to earl

A prehistory of violence : Evidence of violence related skull trauma in southern Sweden, 2300-1100 BCE

Warriors and warfare have become common themes within Bronze Age archaeology the past 10 -20 years. Recent reporting of Neolithic and Bronze Age massacres and battlefields in Germany supports endemic violence in these regions. But what about in southern Scandinavia? This paper explores the evidence of violence related skull trauma from a pooled sample of 257 individuals from 40 different localitie

Anti-inflammatory treatment after cataract surgery in Sweden : Changes in prescribing patterns from 2010 to 2017

Aims To investigate changes in the prescribing patterns of postoperative eye drops following cataract surgery in Sweden from 2010 to 2017. Methods Data from cataract procedures registered in the National Cataract Register during the month of March from 2010 to 2017 were record linked and sent to the Swedish Prescribed Drug Register, which allowed us to determine which eye drops the patients had ob

A Predictive Model of Antibody Binding in the Presence of IgG-Interacting Bacterial Surface Proteins

Many bacteria can interfere with how antibodies bind to their surfaces. This bacterial antibody targeting makes it challenging to predict the immunological function of bacteria-associated antibodies. The M and M-like proteins of group A streptococci (GAS) exhibit IgGFc-binding regions, which they use to reverse IgG binding orientation depending on the host environment. Unraveling the mechanism beh

Mathematical Model of Glucagon Kinetics for the Assessment of Insulin-Mediated Glucagon Inhibition During an Oral Glucose Tolerance Test

Glucagon is secreted from the pancreatic alpha cells and plays an important role in the maintenance of glucose homeostasis, by interacting with insulin. The plasma glucose levels determine whether glucagon secretion or insulin secretion is activated or inhibited. Despite its relevance, some aspects of glucagon secretion and kinetics remain unclear. To gain insight into this, we aimed to develop a

Hybrid Accretion of Carbonaceous Chondrites by Radial Transport across the Jupiter Barrier

Understanding the origin of chondritic components and their accretion pathways is critical to unraveling the magnitude of mass transport in the protoplanetary disk, as well as the accretionary history of the terrestrial planet region and, by extension, its prebiotic inventory. Here we trace the heritage of pristine components from the relatively unaltered CV chondrite Leoville through their mass-i

Identifying the Drivers of Spatial Taxonomic and Functional Beta-Diversity of British Breeding Birds

Spatial variation in community composition may be driven by a variety of processes, including environmental filtering and dispersal limitation. While work has been conducted on the relative importance of these processes on various taxa and at varying resolutions, tests using high-resolution empirical data across large spatial extents are sparse. Here, we use a dataset on the presence/absence of br

Evolution of P-wave indices during long-term follow-up as markers of atrial substrate progression in arrhythmogenic right ventricular cardiomyopathy

AIMS: Patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) have increased prevalence of atrial arrhythmias indicating atrial involvement in the disease. We aimed to assess the long-term evolution of P-wave indices as electrocardiographic (ECG) markers of atrial substrate during ARVC progression. METHODS AND RESULTS: We included 100 patients with a definite ARVC diagnosis according

Genetic relatedness of Streptococcus dysgalactiae isolates causing recurrent bacteraemia

Introduction.Streptococcus dysgalactiae subspecies equisimilis (SDSE) is becoming increasingly recognized as an important human pathogen. Recurrent bacteremia with SDSE has been described previously.Aim. The aims of the study were to establish the genetic relatedness of SDSE isolates with emm-type stG643 that had caused recurrent bacteraemia in three patients and to search for signs of horizontal