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Intestinal preservation injury : A comparison between rat, porcine and human intestines

Advanced preservation injury (PI) after intestinal transplantation has deleterious short-and long-term effects and constitutes a major research topic. Logistics and costs favor rodent studies, whereas clinical translation mandates studies in larger animals or using human material. Despite diverging reports, no direct comparison between the development of intestinal PI in rats, pigs, and humans is

Addressees are sensitive to the presence of gesture when tracking a single referent in discourse

Production studies show that anaphoric reference is bimodal. Speakers can introduce a referent in speech by also using a localizing gesture, assigning a specific locus in space to it. Referring back to that referent, speakers then often accompany a spoken anaphor with a localizing anaphoric gesture (i.e., indicating the same locus). Speakers thus create visual anaphoricity in parallel to the anaph

Optimal power and efficiency of single quantum dot heat engines : Theory and experiment

Quantum dots (QDs) can serve as near perfect energy filters and are therefore of significant interest for the study of thermoelectric energy conversion close to thermodynamic efficiency limits. Indeed, recent experiments in [Nat. Nano. 13, 920 (2018)1748-338710.1038/s41565-018-0200-5] realized a QD heat engine with performance near these limits and in excellent agreement with theoretical predictio

Artificial neural network models to predict nodal status in clinically node-negative breast cancer

Background: Sentinel lymph node biopsy (SLNB) is standard staging procedure for nodal status in breast cancer, but lacks therapeutic benefit for patients with benign sentinel nodes. For patients with positive sentinel nodes, individualized surgical strategies are applied depending on the extent of nodal involvement. Preoperative prediction of nodal status is thus important for individualizing axil

Pituitary Metastases : A Nationwide Study on Current Characteristics with Special Reference to Breast Cancer

Objective To investigate the contemporary presentation of pituitary metastases. Patients Thirty-eight patients diagnosed with pituitary metastases from 1996 to 2018 in Sweden. Methods Pituitary metastases were confirmed by histopathology (n = 27) or considered highly likely according to radiological findings, including rapid tumor progression (n = 11). Medical records were reviewed and sellar imag

Diagnostik och behandling av akuta skafoideumfrakturer

This article suggests algorithms for diagnosis and treatment of scaphoid fractures. A clinical suspected scaphoid fracture without signs of fracture on conventional radiographs should have a supplementary MRI done within 5-7 days. Displaced fractures and all proximal fractures should be classified by CT. Fracture union should be evaluated by CT. 90 procent of non- or minimally displaced waist frac

Multidisciplinärt endokarditteam på plats i Skåne - Första årets erfarenhet visar riktningen framåt

International guidelines recommend that the treatment of patients with infective endocarditis (IE) should be directed by a multidisciplinary endocarditis team. The aim of this study was to describe the first-year experience of multidisciplinary rounds by the endocarditis team in Scania, Sweden. This was a retrospective study on all possible and definitive IE episodes that were assessed by the endo

Complementary bound on the W′ mass from Higgs boson to diphoton decays

Using the left-right symmetric model as an illustrative example, we suggest a simple and straightforward way of constraining the W′ mass directly from the decay of the Higgs boson to two photons. The proposed method is generic and applicable to a diverse range of models with a W′-boson that couples to the Standard Model-like Higgs boson. Our analysis exemplifies how the precision measurement of th

Polypoidal Choroidal Vasculopathy Associate With Diminished Regulatory T Cells That Are Polarized Into a T Helper 2-Like Phenotype

Purpose: To investigate possible roles of T helper (Th) cells, regulatory T cells (Tregs), and the recently mapped Th-like Tregs in patients with polypoidal choroidal vasculopathy (PCV). Methods: In this prospective case-control study, we obtained fresh venous blood from patients with PCV (n = 24), age-matched healthy controls (n = 32), and patients with neovascular AMD (n = 45). All participants

Babesia-infektion kan vara vanligare i Sverige än vi tidigare trott - Parasiten kan spridas via fästingar och blodtransfusion

Babesia är en malarialiknande parasit som är välkänd inom veterinärmedicinen och som sprids med fästingar till människor samt som möjlig transfusionssmitta. Symtom kan vara feber, trötthet och muskelvärk, men hos immunsupprimerade patienter eller vid rubbad mjältfunktion kan organsvikt och livshotande sjukdom snabbt uppkomma. I USA rapporteras drygt 2 000 fall per år. En ny studie från Sydsverige Babesia is a malaria-like, intraerythrocytic parasite with more than 100 different species. It is a zoonosis and some of the species are transmitted to humans by ticks and also as a possible transfusion-transmitted infection. In Sweden the disease has been well known in veterinary medicine for a long time, but only a few but severe cases have been published in humans during the last decades. Commo

Laser-based gas absorption spectroscopy in decaying hip bone : water vapor as a predictor of osteonecrosis

Affluent blood flow through a complicated net of vessels supplies skeletal bone tissue with oxygen and nutrients. Due to accidental events or physiological processes, the blood supply might be deficient or even disrupted, and the healthy bone decays in a process that, for the hip location, is denoted as osteonecrosis of the femoral head (ONFH) or avascular femoral head necrosis. Early diagnosis is

Repair of bone erosions in rheumatoid arthritis : a systematic literature review

Objective: The aim of this study was to review the literature to identify studies reporting repair of erosions in rheumatoid arthritis (RA). Method: A systematic literature search for publications on the repair of erosions was performed in PubMed and Embase, limited to human adults and published in English. Titles, abstracts, and full reports of articles identified were screened by the first autho

Oral insulin therapy for primary prevention of type 1 diabetes in infants with high genetic risk : The GPPAD-POInT (global platform for the prevention of autoimmune diabetes primary oral insulin trial) study protocol

Introduction The POInT study, an investigator initiated, randomised, placebo-controlled, double-blind, multicentre primary prevention trial is conducted to determine whether daily administration of oral insulin, from age 4.0 months to 7.0 months until age 36.0 months to children with elevated genetic risk for type 1 diabetes, reduces the incidence of beta-cell autoantibodies and diabetes. Methods

Association between cerebral microbleeds and hypertension in the Swedish general population “Good Aging in Skåne” study

Cerebral microbleeds (CMB) on MRI are frequent in healthy aging individuals but precede ischemic and hemorrhagic stroke and dementia. Different etiologies have been suggested for nonlobar CMB, which have a stronger connection to hypertension (HT) than do lobar CMB. This study aimed to investigate the prevalence of CMB and the association between nonlobar/lobar CMB and different blood pressure (BP)

Children’s development of semantic verbal fluency during summer vacation versus during formal schooling

Purpose: Children’s results on school-related achievements tests, such as aspects of math, reading and writing, have been shown to decline following a lengthy summer vacation. Few studies have investigated whether this also applies to vocabulary skills. The purpose of this study is to investigate how lexical organization and retrieval, assessed by a semantic verbal fluency (SVF) task, develops dur