Published 6 December 2020 We investigated use of the six major H1-antihistamines (cetirizine, clemastine, desloratadine, ebastine, fexofenadine and loratadine) and breast cancer-specific and overall mortality in a nation-wide register-based study of all 61,627 Swedish women diagnosed with breast cancer 2006–2013. Both peri- and post-diagnostic antihistamine use was analyzed using Cox regression mo

https://www.lupop.lu.se/article/desloratadine-and-loratadine-stand-out-among-common-h1-antihistamines-association-improved-breast - 2025-04-27

Published 7 December 2020 Cognitive function is an important outcome measure in patients with brain tumor, providing information about the patient’s clinical situation, treatment effects and possible progressive disease. The aim of this longitudinal study was to evaluate effects of the currently used radiation and chemotherapy treatment on cognitive function and to investigate associations between

https://www.lupop.lu.se/article/longitudinal-study-cognitive-function-glioma-patients-treated-modern-radiotherapy-techniques-and - 2025-04-27

Published 7 December 2020 Unacceptable pain was frequent. At the 15 year follow-up visit, 34% had unacceptable pain. Patients with unacceptable pain had, compared with patients with tolerable pain, significantly more disease activity, worse patient global assessment, and worse function on the Health Assessment Questionnaire and Signals of Functional Impairment, but the degree of joint destruction

https://www.lupop.lu.se/article/unacceptable-pain-barfot-inception-cohort-patients-rheumatoid-arthritis-long-term-study - 2025-04-27

Published 8 December 2020 An increasing number of people will live with disabilities in their homes and consequently, the need for home-based interventions will increase. Housing adaptations (HAs) are modifications to the physical home environment with the purpose to enhance independence for a heterogeneous group of people. Increasing the knowledge of the characteristics of HA clients by exploring

https://www.lupop.lu.se/article/identifying-and-validating-housing-adaptation-client-profiles-mixed-methods-study - 2025-04-27

Published 8 December 2020 As institutional forms of political engagement continue to decline, participation in protests steadily become more common. These trends are particularly strong among younger citizens. Previous research indicates that social factors can explain participation in political protests, and that younger citizens’ participation in protests is more affected by social ties than old

https://www.lupop.lu.se/article/young-protester-impact-belongingness-needs-political-engagement - 2025-04-27

Published 9 December 2020 Malmö city, Sweden had 322,574 inhabitants in 2015. We used diagnosis registry, charts, and radiographs of the only city hospital to classify fractures in individuals < 16 years in 2014–2016, and compared these with data from 1950–2006. We used joinpoint regression to analyze time trends and present results as mean annual percentage changes (APC). Differences between peri

https://www.lupop.lu.se/article/time-trends-pediatric-fractures-swedish-city-1950-2016 - 2025-04-27

Published 9 December 2020 Two academic centers in Lithuania and Turkey participated in this retrospective study conducted between November 2018 and July 2019. A total of 100 consecutive patients (22 males, 78 females; mean age 78.9 years; range, 45 to 100 years) with low energy proximal femur fractures admitted for surgery were included in the study. Fracture Risk Assessment tool (FRAX) and the Se

https://www.lupop.lu.se/article/combined-fracture-and-mortality-risk-evaluation-stratifying-treatment-hip-fracture-patients - 2025-04-27

Published 10 December 2020 Recent improvements in life expectancy in many countries stem from reduced mortality from cardiovascular disease and cancer above the age of 60. This is the combined result of decreased incidence and improved survival among those with disease. The latter has led to a higher proportion in the population of people with a past history of disease. This is a group with higher

https://www.lupop.lu.se/article/rise-number-long-term-survivors-different-diseases-can-slow-increase-life-expectancy-total - 2025-04-27

Published 10 December 2020 Global environmental change has degraded ecosystems. Challenges such as climate change, resource depletion (with its huge implications for human health and wellbeing), and persistent social inequalities in health have been identified as global public health issues with implications for both communicable and noncommunicable diseases. This contributes to pressure on health

https://www.lupop.lu.se/article/advancing-global-health-through-environmental-and-public-health-tracking-0 - 2025-04-27

Published 11 December 2020 International patient registries are of particular importance for rare disorders, as they may contribute to overcome the lack of knowledge derived from low number of patients and limited awareness of these diseases, and help to learn more about their geographical or population-based specificities, which is relevant for research purposes and for promoting better standards

https://www.lupop.lu.se/article/creation-and-implementation-european-registry-patients-mcardle-disease-and-other-muscle-glycogenoses - 2025-04-27

Published 11 December 2020 Dominant mutations in valosin-containing protein (VCP) gene cause an adult onset inclusion body myopathy, Paget’s disease of bone, and frontotemporal dementia also termed multisystem proteinopathy (MSP). The genotype-phenotype relationships in VCP-related MSP are still being defined; in order to understand this better, we investigated the phenotypic diversity and pattern

https://www.lupop.lu.se/article/phenotypic-diversity-international-cure-vcp-disease-registry - 2025-04-27

Published 12 December 2020 The COVID-19 pandemic may have severe impact on mental health, and concerns have been raised about potentially increased online behavior and possibly increased gambling problems, such as in sports bettors at risk of transfer to even riskier forms of gambling during sports lock-down. Given the need for objective data about gambling behavior during the pandemic, the presen

https://www.lupop.lu.se/article/impact-covid-19-online-gambling-general-population-survey-during-pandemic - 2025-04-27

Published 12 December 2020 Survival data for pancreatic cancer are usually based on actuarial calculations and actual long-term survival rates are rarely reported. Here we use population-level data from the Surveillance, Epidemiology, and End Results program for patients with microscopically confirmed pancreatic ductal adenocarcinoma diagnosed from 1975 to 2011. A total of 84,275 patients with at

https://www.lupop.lu.se/article/actual-5-year-survivors-pancreatic-ductal-adenocarcinoma-based-real-world-data - 2025-04-27

Published 13 December 2020 The aim of this study was to investigate the appearance of a disturbed oropharyngeal microbiota during hospitalization and explore the patient characteristics that maybe associated with such a disturbance. Oropharyngeal swabs were collected from 134 patients at hospital admission and every 3–4 days thereafter. The samples were cultivated to determine the presence of a di

https://www.lupop.lu.se/article/disturbance-oropharyngeal-microbiota-relation-antibiotic-and-proton-pump-inhibitor-medication-and - 2025-04-27

Published 13 December 2020 Only one fifth of children aged 11–17 years are physically active for 60 min (min)/day. As physical activity (PA) levels track from childhood to adulthood, it is important to establish healthy PA behavior early in life. This study aims to evaluate whether daily school PA is associated with objectively measured PA independently of other socioecological factors. This study

https://www.lupop.lu.se/article/daily-school-physical-activity-associated-higher-level-physical-activity-independently-other - 2025-04-27

Published 14 December 2020 The Swedish Quality Register for Inflammatory Bowel Disease (SWIBREG) contains clinical data for the study of inflammatory bowel disease (IBD). The Epidemiology Strengthened by histoPathology Reports in Sweden (ESPRESSO) cohort was recently established for the study of gastrointestinal histopathology. We aimed to develop and validate a histology score from ESPRESSO using

https://www.lupop.lu.se/article/novel-method-quantifying-intestinal-inflammatory-burden-inflammatory-bowel-disease-using-register - 2025-04-27

Published 14 December 2020 Read more at Current national hand surgery registries worldwide - PubMed (nih.gov)

https://www.lupop.lu.se/article/current-national-hand-surgery-registries-worldwide - 2025-04-27

Published 15 December 2020 We are living in a multi-omics era of systems epidemiology. Quantitative high-throughput metabolomics and lipidomics have resulted in hundreds of molecular measures for up to tens of thousands of people in multiple cohorts and biobanks. Extensive and complex data create significant challenges for statistical analyses. It would therefore be beneficial, not only for omics

https://www.lupop.lu.se/article/epimetal-open-source-graphical-web-browser-tool-easy-statistical-analyses-epidemiology-and - 2025-04-27

Published 15 December 2020 Read more at EuroHeart: European Unified Registries On Heart Care Evaluation and Randomized Trials - PubMed (nih.gov)

https://www.lupop.lu.se/article/euroheart-european-unified-registries-heart-care-evaluation-and-randomized-trials-0 - 2025-04-27

Published 16 December 2020 Read more at Moving breast implant registries forward: Are they FAIR and Functional? - PubMed (nih.gov)

https://www.lupop.lu.se/article/moving-breast-implant-registries-forward-are-they-fair-and-functional - 2025-04-27