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Myogenic Reprogramming of Bone Marrow Derived Cells in a WDmd Deficient Mouse Model.

Lack of expression of dystrophin leads to degeneration of muscle fibers and infiltration of connective and adipose tissue. Cell transplantation therapy has been proposed as a treatment for intractable muscle degenerative disorders. Several reports have demonstrated the ability of bone-marrow derived cells (BMDC) to contribute to non-haematopoietic tissues including epithelium, heart, liver, skelet

Effects of Opioids on Breathlessness and Exercise Capacity in Chronic Obstructive Pulmonary Disease: A Systematic Review.

Patients with chronic obstructive pulmonary disease commonly suffer from breathlessness, deconditioning, and reduced health-related quality of life (HRQL) despite best medical management. Opioids may relieve breathlessness at rest and on exertion in COPD. We aimed to estimate the efficacy and safety of opioids on refractory breathlessness, exercise capacity, and HRQL in COPD.

Respondent-driven sampling in a syringe exchange setting.

Aims: Respondent-driven sampling is a research technique, new to the Scandinavian setting, used in hard-to-reach populations, such as subjects at risk for HIV, including drug users. This study aimed to evaluate the use of respondent-driven sampling originating from syringe exchange clients, as a method to identify 'hidden' drug users without treatment or social service contact. Methods: Nine heroi

Orthostatic hypotension predicts all-cause mortality and coronary events in middle-aged individuals (The Malmo Preventive Project).

Aims Orthostatic hypotension (OH) has been linked to increased mortality and incidence of cardiovascular disease in various risk groups, but determinants and consequences of OH in the general population are poorly studied. Methods and results Prospective data of the Swedish 'Malmö Preventive Project' (n = 33 346, 67.3% men, mean age 45.7 +/- 7.4 years, mean follow-up 22.7 +/- 6.0 years) were analy

Klagomålshantering – ett led i att höja kvaliteten eller prat om bagateller?

På kommunernas hemsidor uppmanas äldre att klaga och komma med synpunkter. Klagomål beskrivs som ett värdefullt led för att förbättra verksamheten. Men hanteringen är rörig och klagomålen bagatelliseras av ansvariga chefer, visar forskning från Hälsohögskolan i Jönköping. ”De klagar mest på småsaker, att hemtjänsten inte kommer ibland och så där”, sade en av de socialchefer jag intervjuade i mitt

Late coronary complications after arterial switch operation and their treatment.

OBJECTIVES:: To report the late coronary complications and their treatment after ASO. BACKGROUND:: Asymptomatic patients after arterial switch operation (ASO) may have coronary ostial stenosis or obstruction. METHODS:: Since 1980, 279 patients were operated with ASO. At the time of preparing this article, selective follow-up coronary angiograms were done on 81 patients. RESULTS:: Coronary stenosis

Changes in proteasome structure and function caused by HAMLET in tumor cells.

BACKGROUND: Proteasomes control the level of endogenous unfolded proteins by degrading them in the proteolytic core. Insufficient degradation due to altered protein structure or proteasome inhibition may trigger cell death. This study examined the proteasome response to HAMLET, a partially unfolded protein-lipid complex, which is internalized by tumor cells and triggers cell death. METHODOLOGY/PRI

Return to Action

Return to Action: Critical comments on Bjørnar Olsens key-note article, "After Interpretation: Remembering Archaeology"

Including greenhouse gas emissions during benchmarking of wastewater treatment plant control strategies

The main objective of this paper is to demonstrate how greenhouse gas (GHG) emissions can be quantified during the evaluation of control strategies in wastewater treatment plants (WWTP). A modified version of the IWA Benchmark Simulation Model No 2 (BSM2G) is hereby used as a simulation case study. Thus, the traditional effluent quality index (EQI), operational cost index (OCI) and time in violati