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Pseudo-rotation mechanism for fast olefin exchange and substitution processes at orthometalated C,N-complexes of platinum(II)

Bridge splitting in chloroform of the orthometalated chloro-bridged complex [Pt(mu-Cl)(2-Me2NCH2C6H4)](2) (1), with ethene, cyclooctene, allyl alcohol and phosphine according to 1 + 2L --> 2 [PtCl(2-Me2NCH2C6H4)(L)], where L = C2H4 (3a), C8H14, (3b), CH2CHCH2OH (3c), and PPh3 (4a and 4b) gives monomeric species with L coordinated trans or cis to aryl. With olefins the thermodynamically stable isom

Validity, reliability, and feasibility of durometer measurements of scleroderma skin disease in a multicenter treatment trial

Objective. To determine the validity, reliability, and feasibility of durometer measurements of skin hardness as an outcome measure in clinical trials of scleroderma. Methods. Skin hardness was measured during a multicenter treatment trial for scleroderma using handheld digital durometers with a continuous scale. Skin thickness was measured by modified Rodnan skin score (MRSS). Other outcome data

Intimate partner violence against women, health effects and health care seeking in rural Vietnam

Background: Health effects and health care seeking were investigated among women in rural Vietnam exposed to physical and/or sexual violence from their partner in the past year. The study was conducted within the framework of the demographic surveillance site in Bavi District, Ha Tay Province in northern Vietnam. Methods: Face-to-face interviews based on a questionnaire developed by the WHO for us

Stressful experiences in relation to depth of sedation in mechanically ventilated patients.

n mechanically ventilated patients, sedatives and analgesics are commonly used to ensure comfort, but there is no documented knowledge about the impact of depth of sedation on patients' perception of discomfort. The aim of this study was, therefore, to investigate the relationship between stressful experiences and intensive care sedation, including the depth of sedation. During 18 months, 313 intu

Production of Trichoderma reesei Cel7B and its catalytic core on glucose medium and its application for the treatment of secondary fibers

Application of cellulolytic enzymes for upgrading of secondary fibers has extensively been studied during the last decades. In many cases, research has been carried out with industrial enzyme preparations which often consist of several enzyme components. The presence of various enzymes makes the determination of the role of each of them difficult in changes of pulp and paper properties. Therefore,

Fermentation performance of engineered and evolved xylose-fermenting Saccharomyces cerevisiae strains

Lignocellulose hydrolysate is an abundant substrate for bioethanol production. The ideal microorganism for such a fermentation process should combine rapid and efficient conversion of the available carbon sources to ethanol with high tolerance to ethanol and to inhibitory components in the hydrolysate. A particular biological problem are the pentoses, which are not naturally metabolized by the mai

The relationship between domestic and outward foreign direct investment: The role of industry-specific effects

Previous research has been inconclusive as regards the effect of outward foreign direct investment (FDI) on domestic investments. In this article, we show that this inconclusiveness can be explained at a disaggregated level as a function of the way industries are organized. Based on a simple theoretical framework including monitoring and trade costs, we argue that a complementary relationship can

The Modern RNP World of Eukaryotes

Eukaryote gene expression is mediated by a cascade of RNA functions that regulate, process, store, transport, and translate RNA transcripts. The RNA network that promotes this cascade depends on a large cohort of proteins that partner RNAs; thus, the modern RNA world of eukaryotes is really a ribonucleoprotein (RNP) world. Features of this "RNP infrastructure" can be related to the high cytosolic

Denickling of fatty acid pitch

Unsaturated fatty acids are usually hydrogenated with a nickel catalyst. As a side reaction, nickel dissolves in the fatty acids and forms nickel soaps. On refining the crude fatty acid feedstock by distillation, these nickel soaps are enriched in the bottom fraction (pitch) to a concentration range of 2,500-5,500 ppm. With a heat value comparable to heavy fuel oil, the pitch has been used as fuel

A theoretical investigation of valence and Rydberg electronic states of acrolein

The main features of the ultraviolet spectrum of acrolein have been studied by a multireference perturbative treatment and by a time dependent density functional approach. The valence and Rydberg transition energies have been calculated and the assignment of the experimental bands has been clarified. The different relaxation trends of the three lowest singlet and triplet excited states have been a

Experiences of coercion during investigation and treatment.

According to Swedish legislation (LVM) compulsory treatment shall be decided on if someone, due to ongoing abuse of alcohol, drugs or volatile solvents, is in need of care to overcome abuse and if a voluntary intervention is not possible. Very little research has been conducted in Sweden on this particular legislation with regard to the clients' experiences of entire process from assessment to aft

Preservation of a magnetization carried by magnetite-inclusions during amphibolite grade metamorphic conditions? An example from the Sarek Dykeswarm, Northern Swedish Caledonides

An outcrop consisting of a 608 Myr old sheeted dyke complex and dyke-intruded metasediments has been investigated palaeomagnetically. It is located in the interior of a nappe the basal and upper parts of which suffered penetrative deformation and amphibolite grade metamorphism during the Caledonian orogeny. The only trace from the orogeny at the outcrop is a widely spaced network of brittle and du

MRI and proton spectroscopy in a child with Rasmussen's encephalitis. Case report

The greater sensitivity of magnetic resonance spectroscopy (MRS) compared with MRI to brain abnormalities in Rasmussen's encephalitis was demonstrated in a 3-year-old boy. The patient, with symptoms, signs and morphological findings consistent with Rasmussen's encephalitis, was followed with MRI and MRS over 30 months. That metabolic changes can be disclosed by MRS before the development of sympto

Estimating individual contributions to population growth: evolutionary fitness in ecological time

Ecological and evolutionary change is generated by variation in individual performance. Biologists have consequently long been interested in decomposing change measured at the population level into contributions from individuals, the traits they express and the alleles they carry. We present a novel method of estimating individual contributions to population growth and changes in distributions of

Putting Constructed Regional Advantage into Swedish Practice

This paper presents a study of the pre-history and evolution of a regional innovation system initiative supporting activities at the intersection of traditional food production and modern biotechnology. Drawing on established ideas on the triple helix of industry, university and government and its impact on innovative capacity (as they are formulated in the regional innovation systems approach) an

Spasmolytic flavonols from Artemisia abrotanum

Four flavonols with spasmolytic activity have been isolated from a methanol extract of Artemisia abrotanum L. (Asteraceae), as the principles primarily responsible for the smooth muscle relaxing activity of this plant. The flavonols show a dose-dependent relaxing effect on the carbacholine-induced contraction of guinea-pig trachea, the EC50 values for compounds 1-3 are 20-30 mumol/l while compound