A promising strategy to enable patient stratification for targeted therapies is to monitor the target expression in a tumor by radionuclide molecular imaging. Affibody molecules (7 kDa) are nonimmunoglobulin scaffold proteins with a 25-fold smaller size than intact antibodies. They have shown an apparent potential as molecular imaging probes both in preclinical and clinical studies. Earlier, we fo

Affibody molecules are small scaffold-based affinity proteins with promising properties as probes for radionuclide-based molecular imaging. However, a high reabsorption of radiolabeled Affibody molecules in kidneys is an issue. We have shown that the use of (125)I-3-iodo-((4-hydroxyphenyl)ethyl)maleimide (IHPEM) for site-specific labeling of cysteine-containing Affibody molecules provides high tum

BACKGROUND: Lateral ankle sprain (LAS) is a common and burdensome injury. However, the quality of its management is scant. Nowadays, physiotherapy management of musculoskeletal diseases seems to be generally not based on research evidence. Studies that investigated the knowledge-to-practice gap in LAS management are yet to be carried out. Therefore, this research investigated physiotherapists' kno

This paper provides a comprehensive literature review of preliminary publications on green and sustainable public procurement from the year 2000 until now. The aim of the review is to organise, evaluate and identify patterns and clusters in published articles, providing an overview of the state of the art in green and sustainable public procurement. Classification of the data identified three over

Transitioning from linear to circular production systems requires interactions that include cross-sectoral collaboration in networks. Understanding the role of collaboration within these networks can support the transition to a circular economy. To understand cross-sectoral collaborative endeavors, this paper develops a collaboration framework for circular economy by combining and interlinking thr

Through ultrarelativistic particle collisions at the LHC, it is possible to deconfine quarks and gluons. This deconfinement gives rise to a strongly interacting medium, referred to as the Quark-Gluon Plasma (QGP). One of the earliest proposed and observed signatures of the QGP was the enhanced production of strange hadrons since the medium can thermally produce strange quarks. However, recent stud

Research shows that much of the blame for waste and lost resources can be traced to the design phase. The implementation of Circular Economy (CE) has the potential to reduce waste by encouraging reuse of resources in a closed loop. Given that designers are involved in the design process, this paper investigates whether they are properly equipped to take responsibility for the shift toward CE. A gr

The thesis aims to develop a 3D digital approach to the stylistic and typo-technological study of coroplastic, focusing on small figurines. The case study to test the method is a sample of terracotta statuettes from an assemblage of approximately 2000 statues and figurines found at the beginning of the 20th century in a rural open-air sanctuary at Ayia Irini (Cyprus) by the archaeologists of the S

In small systems with large fluctuations, the classical description of thermodynamics is no longer sufficient which has led to the development of stochastic thermodynamics. One important result from stochastic thermodynamics is that with measurement and feedback it is possible to use those fluctuations to extract work from a single heat bath coupled to the system. This is thanks to the connection

Organizing rural workers has always proved to be a challenge for the labour movement. This was especially the case in Scandinavia where well into the industrial era, labour and property relations in the agricultural countryside remained essentially feudal in character. Nonetheless, and especially in the rich agricultural districts of the southernmost province of Skåne, the Swedish labour movement

The Internet of Things (IoT) is a large network of connected devices. In IoT, devices can communicate with each other or back-end systems to transfer data or perform assigned tasks. Communication protocols used in IoT depend on target applications but usually require low bandwidth. On the other hand, IoT devices are constrained, having limited resources, including memory, power, and computational

The purpose of this study is to examine how teachers’ PCK is expressed in science teaching practice, both from a teacher’s and a student’s perspective. It is a qualitative study of three teachers’ physics classroom lectures in grades 7 and 8. International research has highlighted the impact of teachers on students’ achievement in general and in science education in particular, and several ongoing

Due to the negative environmental impacts along the life cycle of fossil-based plastics, there is an increased interest in the development of biobased and biodegradable plastics. Especially, biodegradable bioplastics possess different material characteristics than fossil-based plastics and can therefore be expected to perform differently during the product use and in end-of-life (EOL) phases. Thus

Temperature and coagulant types have an important impact on the quantity and quality of the residue (sludge) in water and wastewater treatment processes. Temperature influences water viscosity and the distribution of the coagulant in water. Coagulants can promote the agglomeration of fine particles into larger flocs so that they can be more easily separated from the water. Experiments have been co

Background: A new, supposedly more reproducible radiographic classification, set to replace the Tönnis classification of hip dislocations, was proposed in 2015: the International Hip Dysplasia Institute (IHDI) classification. Purpose: To compare the IHDI classification with the Tönnis classification when evaluating the severity of hip dislocations as well as their respective inter- and intra-obser

This chapter examines the nature of the interaction between the Georgian Orthodox Church (GOC) and the state during the pandemic. The article shows how the church’s gradual acknowledgment of the deadly character of the virus coincided with a strict adherence to certain highly risky religious practices (such as communion from the same spoon), while the Georgian government’s stance in defense of pub