Rostrocaudal patterning of the neural tube is a defining event in vertebrate brain development. This process is driven by morphogen gradients which specify the fate of neural progenitor cells, leading to the partitioning of the tube. Although this is extensively studied experimentally, an integrated view of the genetic circuitry is lacking. Here, we present a minimal gene regulatory model for rost

Bakgrund Teknikutvecklingen inom hälso- och sjukvårdsområdet möjliggör ständigt nya och mer avancerade sätt att distansmonitorera och vårda patienter digitalt. Digitaliseringen inom hälso- och sjukvårdsområdet i form av till exempel hälsoapplikationer gör det möjligt för patienter och personal att ha kontakt och kommunicera digitalt med varandra (WHO, 2011). itACiH är ett digitalt system där patie

Bakgrund Framväxten av hälsoapplikationer som gör det möjligt för patienter att kontakta och kommunicera med vårdpersonal digitalt kan förändra hur patienter ser på sin vård och hur de kontaktar vårdpersonalen (WHO, 2011). Digitala system kan också, utifrån sin design, ge förutsättningar för relationscentrerad vård genom att patienterna ges möjlighet att, i samverkan med vårdpersonalen, vara aktiv

One of the most significant obstacles for the every­day use of systems based on Brain­Computer Inter­faces (BCIs) is the tediousness of calibration. Successful improvements on calibration, particularly the time needed and the user­experience, have been made with, e.g., transfer learning, gamification, and task estimation [1, 2, 3]. Inthis work, we present an adaptive approach to BCI systems’ calib

In this study we explore what digitally supported, mobile work in home care nursing may look like in practice. The results show that there is a large degree of self-determination among the nurses when it comes to organizing their work and that the digital systems can lead to an increased complexity. The diverse environment encountered in home care (as compared to the more standardized hospital env

An e-library for standardized chemotherapy regimens has been developed and is, since 2015, available as a national resource for healthcare staff and patients in cancer treatment in Sweden. The library was developed in a user-centered design process and is now evaluated to understand how it is used and if it is used in the intended way. This paper presents the e-library in brief together with preli

The Covid-19 pandemic has fundamentally changed travel patterns to and in major urban regions. Destinations have seen a dramatic shift from overtourism to undertourism. This has led to new challenges for regional destination management organisations (DMOs) as tourists and residents seek green areas in cities and visit adjacent natural reserves. Therefore this research explores how the Covid-19 pan

The Covid-19 pandemic has fundamentally changed travel patterns to and in urban regions. Destinations have seen a dramatic shift from overtourism to undertourism. This research explores how the pandemic has reconceptualised the relationship between the urban and rural. In particular this paper discusses the relationship between media narratives and tourism flows, and the implications for resilienc

Background: Occupational heat exposure can provoke health problems that increase the risk of certain diseases and affect workers’ ability to maintain healthy and productive lives. This study investigates the effects of occupational heat stress on workers’ physiological strain and labor productivity, as well as examining multiple interventions to mitigate the problem. Methods: We monitored 518 full

I Lund innebar pandemin att for­matet för laborationer uppdatera­des – och i slutändan blev bättre.

Background: Arterial ageing is characterised by degradation of elastic fibres and increased stiffness of elastic arteries. Although low lung function and arterial stiffness are strongly related to age, the association between lung function and arterial ageing has not been widely explored. We used a large population-based study of 50-64 year olds to assess the association between lung function (mea

This volume discusses the topics of sin, suffering, and evil in the Hebrew Bible. It gathers fresh and innovative perspectives provided by internationally renowned biblical scholars that not only demonstrate ways in which these topics are dealt with in the Hebrew Bible itself, but also map out their lasting impact on human experience of suffering throughout history. Put into dialogue with the thou

This article explores the ways the dynamics of sin, good, andevil may be understood in a technological future characterized by the implementation of artificial intelligence in society. By re-reading the Eden story inGenesis 2–3 in light of current AI-discourse, Scheuer shows how sin, good, andevil are intrinsic to the enterprise of creating an entity that bears the essence ofthe Creator, while at

Wear mechanisms and failure modes were investigated for autoclave-cured, woven carbon fiber-reinforced polymer (CFRP) composite gears in a mesh with a surface-hardened, 42CrMo4 steel pinion. The reference gears (m = 1 mm, b = 2 mm, z = 20) were tested at torque levels ranging from 0.4 Nm to 0.8 Nm. The temperature was monitored with a thermographic camera, while the gear damage and wear volume wer