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Neutron decay width of one-particle resonant levels in deformed nuclei

The neutron partial decay width of one-particle resonant levels that are the bandhead states in odd-N deformed nuclei is estimated in the formalism with a real-energy variable, using the width of one-particle resonance calculated in terms of eigenphase. It is shown that because of the presence of various (lj) components in a given one-particle resonant level of deformed nuclei, the neutron decay w

Two thymidine kinases and one multisubstrate deoxyribonucleoside kinase salvage DNA precursors in Arabidopsis thaliana.

Deoxyribonucleotides are the building blocks of DNA and can be synthesized via de novo and salvage pathways. Deoxyribonucleoside kinases (dNKs) salvage deoxyribonucleosides by transfer of a phosphate group to the 5' of a deoxyribonucleoside. This salvage pathway is well characterized in mammals but in contrast little is known about how plants salvage deoxyribonucleosides. We show that during salva

A Possible Mechanism behind Autoimmune Disorders Discovered By Genome-Wide Linkage and Association Analysis in Celiac Disease

Celiac disease is a common autoimmune disorder characterized by an intestinal inflammation triggered by gluten, a storage protein found in wheat, rye and barley. Similar to other autoimmune diseases such as type 1 diabetes, psoriasis and rheumatoid arthritis, celiac disease is the result of an immune response to self-antigens leading to tissue destruction and production of autoantibodies. Common d

Comparative Study of Estonian Swedish Voiceless Laterals: Are Voiceless Approximants Fricatives?

Are voiceless approximants categorically distinct from voiceless fricatives? We address this question by means of acoustic analysis of voiceless laterals in Icelandic, Welsh, and the endangered variety Estonian Swedish. All three have a voiceless lateral functioning in contrast to a voiced lateral approximant. The analysis focused on duration – including any period of voicing (‘pre-voicing’) just

Decarbonising industry in Sweden

This report analyses the technical opportunities for a complete decarbonisation of the basic material industry in Sweden by 2050. From this assessment, the report discusses policy implications for the industry sector given the overall framework set by the ongoing international climate negotiations. Relying on current production systems and applying “end-of-pipe” solutions will be insufficient to

Optimal cuts and partitions in tree metrics in polynomial time

We present a polynomial time dynamic programming algorithm for optimal partitions in the shortest path metric induced by a tree. This resolves, among other things, the exact complexity status of the optimal partition problems in one-dimensional geometric metric settings. Our method of solution could be also of independent interest in other applications. We discuss also an extension of our method t

Probing hydrogen positions in hydrous compounds: information from parametric neutron powder diffraction studies

We demonstrate the extent to which modern detector technology, coupled with a high flux constant wavelength neutron source, can be used to obtain high quality diffraction data from short data collections, allowing the refinement of the full structures (including hydrogen positions) of hydrous compounds from in situ neutron powder diffraction measurements. The in situ thermodiffractometry and contr

Proteolytic Activity of Prostate-Specific Antigen (PSA) towards Protein Substrates and Effect of Peptides Stimulating PSA Activity.

Prostate-specific antigen (PSA or kallikrein-related peptidase-3, KLK3) exerts chymotrypsin-like proteolytic activity. The main biological function of PSA is the liquefaction of the clot formed after ejaculation by cleavage of semenogelins I and II in seminal fluid. PSA also cleaves several other substrates, which may explain its putative functions in prostate cancer and its antiangiogenic activit

Perspektivisk Textanalys (PTA): Manual till Vertex med danskt material

The present work is based on the Kantian (AaO)-axiom and conceptualised as textbook. As scientific method in the true sense of the notion science, the Vertex version of Perspective Text Analysis represents a completely new approach to text-based studies. The core of Vertex is introduced by means of instructions to a stepwise procedure. The steps are richly illustrated. The inter-lingual character

Stat1 activation attenuates IL-6 induced Stat3 activity but does not alter apoptosis sensitivity in multiple myeloma

Background: Multiple myeloma (MM) is at present an incurable malignancy, characterized by apoptosis-resistant tumor cells. Interferon (IFN) treatment sensitizes MM cells to Fas-induced apoptosis and is associated with an increased activation of Signal transducer and activator of transcription (Stat)1. The role of Stat1 in MM has not been elucidated, but Stat1 has in several studies been ascribed a

Spottier Targets Are Less Attractive to Tabanid Flies: On the Tabanid-Repellency of Spotty Fur Patterns

During blood-sucking, female members of the family Tabanidae transmit pathogens of serious diseases and annoy their host animals so strongly that they cannot graze, thus the health of the hosts is drastically reduced. Consequently, a tabanid-resistant coat with appropriate brightness, colour and pattern is advantageous for the host. Spotty coats are widespread among mammals, especially in cattle (

Deep sequencing extends the diversity of human papillomaviruses in human skin.

Most viruses in human skin are known to be human papillomaviruses (HPVs). Previous sequencing of skin samples has identified 273 different cutaneous HPV types, including 47 previously unknown types. In the present study, we wished to extend prior studies using deeper sequencing. This deeper sequencing without prior PCR of a pool of 142 whole genome amplified skin lesions identified 23 known HPV ty

A microscopic investigation of miR-34c and miR-205 in Prostate Cancer

Popular Abstract in Swedish Förr trodde man att de delar av genomet som inte uttrycks till proteiner är oviktiga, eftersom man trodde att det nästan uteslutande är proteinerna som utför de nödvändiga funktionerna i cellen. Man kände till att DNA och RNA innehåller information om hur proteiner ska se ut och när de ska uttryckas, men man kände bara till ett fåtal andra uppgifter som RNA har i cellenThe complex genetics of cancer allows tumors to grow and spread undeterred by the control mechanisms of the cell. The importance of protein-coding genes in tumorigenesis is well established. Recently, microRNAs (miRNAs) have emerge as key regulator of development and cellular processes such as differentiation, cell growth and cell death; processes closely linked to cancer. The aim of this thesis w

Propionibacterium acnes and its phages

Popular Abstract in Swedish Mikroorganismer finns överallt! De klarar av att överleva i extrema miljöer, extrema pH, extrema temperaturer och kan motstå strålning och gift i doser som vi inte skulle överleva. Framförallt klarar mikroorganismer av att överleva i en specifik extrem miljö - människan. Hundratals olika mikroorganismer bor på och i oss, i ett antal som långt överskrider vårt eget cellaMicroorganisms are everywhere! They can tolerate many diverse extreme environments, such as the human body. Even though many of us might associate the word microorganism with infections and disease, most are actually either harmless or even beneficial for us. Those commensals often fight off more dangerous bacteria and might also directly benefit their host. The human skin harbors several differen

Impaired vascular function after exposure to diesel exhaust generated at urban transient running conditions

Background: Traffic emissions including diesel engine exhaust are associated with increased respiratory and cardiovascular morbidity and mortality. Controlled human exposure studies have demonstrated impaired vascular function after inhalation of exhaust generated by a diesel engine under idling conditions. Objectives: To assess the vascular and fibrinolytic effects of exposure to diesel exhaust g

The 'Field' in the Age of Intervention: Power, Legitimacy, and Authority Versus the 'Local'

This article highlights the semantic and socio-political meaning of the 'field' as it is used in both academic research and policy practices: as a geographic and material space related to forms of intervention in International Relations (IR), and not as a disciplinary space. We argue that the notion of the field' carries colonial baggage in terms of denoting 'backwardness' and conflictual practice