Objective: To study chronic widespread pain (CWP) over time in patients with spondyloarthritis (SpA), and to identify risk factors for development and persistence of CWP. Methods: In this cohort study with baseline and 2.5 year follow-up postal surveys, patients with ankylosing spondylitis (AS) and undifferentiated spondyloarthritis (USpA) (47% women) answered questions regarding pain, and were ca

Hippo signaling is a key regulator of organ size, tissue hemostasis and regeneration. Dysregulation of the Hippo pathway has been recognized in a variety of human cancers, including pancreatic cancer. YES-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) are the two major downstream effectors of the Hippo pathway. YAP and TAZ have been found to promote pancreati

While scholars commonly assume that Global Governance Institutions (GGIs) need legitimacy to perform effectively, there are few systematic empirical studies assessing the consequences of legitimacy (or the lack thereof) for the functioning of GGIs. Inspired by the new institutionalism in organization theory, which predicts that more legitimate organizations will get more resources than illegitimat

The existing information supports the use of this material as described in this safety assessment. Methyl 2-nonenoate was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data from read-across analog ethyl trans-2,cis-4-decadienoate (CAS # 3025-30-7) show that methy

Background: Although women with fear of birth often report negative birth experiences, few studies have focused on their experiences in the long term. The aim of this study was to compare birth experiences a year after childbirth in two groups of women receiving treatment for experiencing fear of birth during pregnancy. Methods: As part of the U-CARE: Pregnancy Trial, a prospective multicenter ran

Eight different generations of dolerite dykes crosscutting the Paleoproterozoic basement in West Africa and one in South America were dated using the high precision U–Pb TIMS method on baddeleyite. Some of the individual dykes reach over 300Â km in length and they are considered parts of much larger systems of mafic dyke swarms representing the plumbing systems for large igneous provinces (LIPs).

Phenomenology strives for the actualization of contact. As a way of study it seeks to meet the things of the world as those things are in themselves and so describe them. Geography studies the earth as the dwelling place of man. As one of its tasks, it seeks to understand how people live in relation to everyday places, spaces, and environments. A phenomenological geography borrows from both fields

Aim: The mechanisms of plant trait adaptation and acclimation are still poorly understood and, consequently, lack a consistent representation in terrestrial biosphere models (TBMs). Despite the increasing availability of geo-referenced trait observations, current databases are still insufficient to cover all vegetation types and environmental conditions. In parallel, the growing number of continuo

Atopic dermatitis (AD) is a common inflammatory skin disease that affects both children and adults, including a large number of adults of reproductive age. Several guidelines for the treatment of AD exist, yet specific recommendations for the treatment of pregnant or lactating women and for adults planning to have a child are often lacking. This position paper from the European Task force on Atopi

During 1984–2009, 664 adults and 1,944 goslings of Greylag Geese Anser anser were neck-banded in south-west Scania, Sweden. After hatching the area was careful-ly searched for marked geese, giving more than 100,000 re-sightings. Of those marked as goslings 71% survived the first year, 52% the second year, and the oldest bird recorded was 25 years. About 50% of the survivors were recruited into the

The recently introduced method of `signal apparition' offers a fundamentally different approach to separation of multiple interfering sources, by using a periodic sequence of source signatures along one source line. This leads to exact separation of signals in diamond-shaped regions of the frequency-wavenumber domain which are twice as large compared to those recovered by other methods. In this pa

The need to study the effects of technology and science in development has been increasingly emphasized in recent years. At the same time, India and China have emerged on the world scene as large developing countries with rich, often contrasting, experiences of the application of technology and science to development. Comparative research on the Indian and Chinese experiences thus carries a great

The need to study the effects of technology and science in development has been increasingly emphasized in recent years. At the same time, India and China have emerged on the world scene as large developing countries with rich, often contrasting, experiences of the application of technology and science to development. Comparative research on the Indian and Chinese experiences thus carries a great

Traditional recoveries of ringed Greylag Geese Anser anser from different regions in Sweden have been analyzed to compare the migration patterns from a number of different areas. During the years up to and including 2012, 7210 Greylag Geese were marked with metal rings from the Swedish Ringing Centre, yielding 1398 recoveries. After exclusion of local recoveries in the ringing area, 924 recoveries

Scania in southern Sweden is an important staging and wintering province for the Bean Goose Anser fabalis, especially for the Taiga form A. f. fabalis. Based on counts in October, November and January 1977/1978– 2016/2017, and observations of neck-banded individuals, the changes in local distribution are described. When the counts started, large numbers were counted already in October, but autumn

On 27 May 2015, a Green Warbler Phylloscopus nitidus was caught and ringed at Blåvand Bird Observatory, the westernmost point in Denmark. The species is challenging to identify on morphological basis alone, and the bird’s identity was confirmed with phylogenetic analyses of mitochondrial DNA sequences. This constitutes the first record of Green Warbler in Denmark, the third record in Fennoscandia

Objectives: Mild and moderate dehydration adversely affect mood and cognitive function. During dehydration, hypertonic hypovolemia activates both osmo- and baro-receptors but it is not known which physiological pathway is associated with degraded mood state. This study examined the acute effect of osmoreceptor stimulation on mood.Methods: Sixty healthy adults (50% females, 30 ± 1 y; BMI: 26.9 ± 4.