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Charting the human lung with inhaled nanoparticles : Development of AiDA - a new diagnostic technique for respiratory disease

Changes to the smallest structures of the distal lung are often the first sign of severe respiratory disease, but to date methods to detect and quantify these changes are limited. Chronic obstructive pulmonary disease (COPD) is currently estimated to be the third most common cause of death worldwide, but is to a large extent under-diagnosed, especially at early stages. This thesis explores a new m

About Not Understanding the System : Ignorance as an Obstacle to a Meaningful Life in Sweden

This presentation builds on several ethnographic fieldworks (2011-2015) in southern Sweden on people who have Palestinian background as well as my on-going informal involvement with Palestinian networks. The field material includes about 35 qualitative interviews, numerous informal discussions and participant observations of political events (mostly demonstrations and lectures) and people’s daily This presentation builds on several ethnographic fieldworks (2011-2015) in southern Sweden on people who have Palestinian background as well as my on-going informal involvement with Palestinian networks. The field material includes about 35 qualitative interviews, numerous informal discussions and participant observations of political events (mostly demonstrations and lectures) and people’s daily

Modeling of structural cables

For many applications, including future giant telescopes, there is increased interest in structural cables. Usually integrated models, i.e. combined models of structures, optics and control systems are used for modeling of telescopes. Performance of structural cables is non-linear, so often a linearization is needed to include cable models in integrated models of telescopes. We present two differe

A taxonomy of deviant encodings

The main objective of this paper is to design a common background for various philosophical discussions about adequate conceptual analysis of “computation”.

Infection events in the fungus-nematode system

Infection of vermiform nematodes by nematophagous fungi generally follows the same route whether the nematode is captured in adhesive traps of predatory fungi or mediated by conidia of endoparasites. A successful infection always results in complete digestion of the nematode corpus. The total time for the infection process varies between fungal species and also between species of nematodes being p

Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats

Dopamine (DA) neurons derived from human embryonic stem cells (hESCs) are a promising unlimited source of cells for cell replacement therapy in Parkinson's disease (PD). A number of studies have demonstrated functionality of DA neurons originating from hESCs when grafted to the striatum of rodent and non-human primate models of PD. However, several questions remain in regard to their axonal outgro

Computer simulation analysis of source-detector position for percutaneously measured O2-gas signal in a three-dimensional preterm infant lung

Further improvements in the clinical care of our most vulnerable patients-preterm infants-are needed. Novel diagnostic and surveillance tools facilitate such advances. The GASMAS technique has shown potential to become a tool to, noninvasively, monitor gas in the lungs of preterm infants, by placing a laser source and a detector on the chest wall skin. It is believed that this technology will beco

Test-retest reliability of the life satisfaction questionnaire (LISAT-11) and association between items in individuals with chronic stroke

Objective: To evaluate the test–retest reliability of the Life Satisfaction Questionnaire (LiSat-11) and the association between items in individuals with chronic stroke. Design: Test–retest design. Subjects: Forty-five individuals (mean age 65 years) with mild to moderate disability at least 6 months post-stroke. Methods: LiSat-11, which includes 1 global item”Life as a whole” and 10 domain-speci

Effects of Treatment with Adalimumab on Blood Lipid Levels and Atherosclerosis in Patients with Rheumatoid Arthritis

Background: Treatment with tumor necrosis factor inhibitors for rheumatoid arthritis has been associated with a decreased risk of cardiovascular disease in observational studies. There are conflicting data on the influence of tumor necrosis factor inhibitors on lipid levels. Objectives: To evaluate the effect of treatment with adalimumab on blood lipid levels, lipoproteins, and atherosclerosis of

Three-dimensional pelvic incidence is much higher in (thoraco)lumbar scoliosis than in controls

Purpose: The pelvic incidence (PI) is used to describe the sagittal spino-pelvic alignment. In previous studies, radiographs were used, leading to less accuracy in establishing the three-dimensional (3D) spino-pelvic parameters. The purpose of this study is to analyze the differences in the 3D sagittal spino-pelvic alignment in adolescent idiopathic scoliosis (AIS) subjects and non-scoliotic contr

Managing Intensity in Knowledge Work: Self-Leadership Practices among Danish Management Consultants

This paper examines the sources of knowledge workers’ work intensity and the self-leading strategies they apply to deal with it. The paper is based on focus group interviews with management consultants in a Danish management consultancy firm. Work intensity was identified as resulting from a combination of: (1) a results-only focus, (2) vagueness, (3) boundaryless work, and (4) low control of the

Flight

Animal flight represents a great challenge and model for biomimetic design efforts. Powered flight at low speeds requires not only appropriate lifting surfaces (wings) and actuator (engine), but also an advanced sensory control system to allow maneuvering in confined spaces, and take-off and landing. Millions of years of evolutionary tinkering has resulted in modern birds and bats, which are achie

Interpolation and Extrapolation of Toeplitz Matrices via Optimal Mass Transport

In this work, we propose a novel method for quantifying distances between Toeplitz structured covariance matrices. By exploiting the spectral representation of Toeplitz matrices, the proposed distance measure is defined based on an optimal mass transport problem in the spectral domain. This may then be interpreted in the covariance domain, suggesting a natural way of interpolating and extrapolatin

Inter-laboratory comparison of channelized hotelling observer computation

Purpose: The task-based assessment of image quality using model observers is increasingly used for the assessment of different imaging modalities. However, the performance computation of model observers needs standardization as well as a well-established trust in its implementation methodology and uncertainty estimation. The purpose of this work was to determine the degree of equivalence of the ch

Tracking and Sensor Fusion in Direction of Arrival Estimation Using Optimal Mass Transport

In this work, we propose new methods for information fusion and tracking in direction of arrival (DOA) estimation by utilizing an optimal mass transport framework. Sensor array measurements in DOA estimation may not be consistent due to misalignments and calibration errors. By using optimal mass transport as a notion of distance for combining the information obtained from all the sensor arrays, we

Immobilized Cells and Organelles : Volume I

Cells and organelles are small units for biochemical synthetic purposes, often the smallest practically feasible unit since they contain coenzyme regenerating system, ordered enzyme sequences, etc.These volumes, besides giving some insight into basic technology (immobilisation procedures, etc.), also sum up the current know-how in this subject area and try to predict some future trends. The term i

Determining the consistency of resolved triplets and fan triplets

The R+-F+-Consistency problem takes as input two sets R+ and R- of resolved triplets and two sets F+ and F- of fan triplets, and asks for a distinctly leaf-labeled tree that contains all elements in R+ ⊂ F+ and no elements in R- ⊂ F- as embedded subtrees, if such a tree exists. This article presents a detailed characterization of how the computational complexity of the problem changes under variou