Essentials Knowledge of genetic regulators of plasma factor VII activating protease (FSAP) levels is limited. We performed a genome-wide analysis of variants influencing FSAP activity in Scandinavian cohorts. We replicated an association for Marburg-1 and identified an association for a HABP2 stop variant. We identified a novel locus near ADCY2 as a potential additional regulator of FSAP activity.

Försvarsadvokaters arbete utspelar sig i emotionellt laddade men emotionellt begränsade situationer. Detta är särskilt påtagligt i brottmålsrättegångar. Upprivna klienter, oförutsebara avbrott, skakande bevis, emotionella målsägande, till och med moralisk misstänksamhet förväntas hanteras på ett korrekt och passande sätt. Den här avhandlingen analyserar hur detta görs i en svensk kontext, med specDefence lawyers’ work takes place in emotionally charged, yet emotionally constraining situations. This is particularly evident in criminal trials. Distressed clients, unforeseeable disruptions, disturbing evidence, emotional plaintiffs and even moral suspicions should all be managed in a proper and appropriate manner. Loyalty Work analyses how this is done in the context of Sweden, with specific

The long-term impact of the Chernobyl accident on the most affected populations in Belarus, Ukraine and the Russian Federation is still evident in terms of a continuing elevated level of thyroid cancer, prominent psychosocial effects, a depressed economy and a low level of well being. Some of these impacts are directly and primarily attributable to exposure to ionising radiation, while others have

At the Rio Earth Summit of 1992 governments undertook to develop and adopt national sustainable development strategies as a key component of implementing the goals of Agenda 21. Only partial progress was reported at the 2002 World Summit in Johannesburg, with uncertainty as to the effectiveness of those strategies that had been introduced. This paper describes a methodology for assessing a country

Environmental assessment (EA)1 systems in the countries-in-transition (CITs) in Central and Eastern Europe, Caucasus and Central Asia have been significantly reformed over the last decade. Considerable research efforts have focused on the degree to which EA in this region conforms to best international practice, functions well and results in environmental and democratic improvements. This article

The Paper describes the main directions and the outcomes of the reform of EA legislation in practice in 27 former socialist countries in the 1990s. During this period, more than 100 legal acts in the field of EA have been introduced and EA has become one of the most widely used environmental policy tools. The process of political and economic transition has significantly influenced the evolution o

The environmental impact assessment (EIA) process has been used in a number of countries since the early 1970s as an instrument of environmental regulation at the planning stage of economic activity. Since the mid-1980s, some of the principle of EIA have been introduced in the USSR's environmental legislation and regulations which has resulted in the development of two distinctive regulatory conce