The interaction between recombinant human cystatin C and the cysteine proteinases papain and actinidin was studied by spectroscopic, kinetic and equilibrium methods. The absorption, near-u.v.c.d. and fluorescence-emission difference spectra for the cystatin C-proteinase interactions were all found to be similar to the corresponding spectra for chicken cystatin. The kinetics of binding of cystatin

An increased prevalence of asthma in cross-country skiers has been reported previously. This study was conducted in order to evaluate the prevalence of asthma among young, elite cross-country skiers in Trondelag, Norway and Jamtland, Sweden. These two regions in central Scandinavia have different climates during the winter season, with a coastal type in Trondelag while Jamtland is characterized by

Objectives: To study diagnostic delay in invasive bladder cancer in a population-based material with long-term follow-up, and to evaluate whether delay in diagnosis affects the risk of bladder cancer death. Material and Methods: In a previous study, 177 patients with invasive bladder cancer (T1-T4) diagnosed in 1988 were investigated with regard to diagnostic delay. A review of all available clini

Popular Abstract in Swedish I mer än tre årtionden har kvinnors situation och främjandet av jämställdhet mellan kvinnor och män lyfts fram inom utvecklingssamarbetet. Bilaterala organisationer har gjort politiska åtaganden och utvecklat strategier, metoder och instrument för att uppnå detta viktiga mål. Som uppföljning på FNs fjärde kvinnokonferens i Peking (1995) är det viktigt att analysera vad Gender equality has been on the development cooperation agenda for more than three decades. Bilateral agencies have developed policies, strategies, methodologies and tools to support achievement of this important goal. Following the Fourth United Nations Conference on Women in Beijing in 1995 it is important to take stock of the progress that has been made, and identify the changes needed for movi

Object. Arterial vasospasm is the most common cause of delayed ischemic neurological deficits (DINDs) and one of the major causes of disability following subarachnoid hemorrhage (SAH). Current management of vasospasm involves intravascular volume expansion and hemodynamic augmentation with the goal of increasing cerebral blood flow (CBF). The purpose of this study was to examine the effects of vol

We investigate the propagation of electromagnetic waves in a cylindrical waveguide with an arbitrary cross section filled with a nonlinear material. The electromagnetic field is expanded in the usual eigenmodes of the waveguide, and the coupling between the modes is quantified. We derive the wave equations governing each mode with special emphasis on the situation with a dominant TE mode. The resu

The human-specific bacterial pathogen Neisseria meningitidis is a major cause of sepsis and/or meningitis. The pili of N. meningitidis interact with CD46, a human cell-surface protein involved in regulation of complement activation. Transgenic mice expressing human CD46 were susceptible to meningococcal disease, because bacteria crossed the blood-brain barrier in these mice. Development of disease

Excited state properties of fluorobenzene, chlorobenzene, bromobenzene, and iodobenzene have been investigated theoretically using multireference CASSCF and CASPT2 methods. Experimentally, chlorobenzene and bromobenzene are known to exhibit one fast dissociation channel, whereas iodobenzene exhibits two fast dissociation channels. The calculations indicate that the chlorobenzene, the bromobenzene,

Objectives To reanalyze randomized controlled trials on the use of umbilical artery Doppler velocimetry in high-risk pregnancies and determine which high-risk pregnancies benefit from the use of Doppler velocimetry, Methods Searching Medline, the Cochrane Library and Embase we found 13 randomized controlled trials on the use of Doppler velocimetry in high-risk pregnancies. Of these, six included p

In this paper, we report the results of a systematic study of the elastic properties of nanosized single-crystal wires and beams of bcc iron. Both tensile and bending stiffnesses have been determined employing molecular statics simulations for specimens of different sizes and three different crystallographic orientations. We also analyze the influence of circular cross sections and rounded edges c

Several genome sequencing projects have recently been completed and the majority of human coding regions have been sequenced. In the next step many of the further studies will concentrate on proteins. Proteomics methods are essential for studying protein expression. activity, regulation and modifications. Bioinformatics is an integral part of proteomics research. The recent developments and applic

Presents an approach to improved performance and flexibility in industrial robotics by means of sensor integration and feedback control in task-level programming and task execution. Also presents feasibility studies in support of the ideas. Discusses some solutions to the problem using six degrees of freedom force control together with the ABB S4CPlus system as an illustrative example. Consider va

An intramolecular NEMO potential is presented for the N-formylglycinamide molecule together with an intermolecular potential for the N-formylglycinamide-water system. The intramolecular N-formylglycinamide potential can be used as a building block for the backbone of polypeptides and proteins. Two intramolecular minima have been obtained. One, denoted as C5, is stabilized by a hydrogen bonded five

Popular Abstract in Swedish Att fasta under ramadan är både en glädje och ett jihad för det muslimska samfundet i Java, och fastan är utan tvekan den mest aktade ritualen i det muslimska Indonesien (och på andra håll i den muslimska världen). Att avhålla sig från mat, dryck och sexuella relationer från gryning till skymning i en hel månad i ett tropiskt klimat - och att fylla nätterna med extra frFASTING DURING THE holy month of Ramadan is both a joy and a jihad for the Islamic community in Java, and it is arguably the most highly esteemed Muslim ritual in Indonesia (and beyond). To be given the opportunity to abstain from food, drink and sexual relations from the early morning hours until sunset during an entire month in a tropical climate - only to fill the nights with additional and sup

Background: The 39 item Parkinson's disease questionnaire (PDQ-39) is the most widely used patient reported rating scale in Parkinson's disease. However, several fundamental measurement assumptions necessary for confident use and interpretation of the eight PDQ-39 scales have not been fully addressed. Methods: Postal survey PDQ-39 data from 202 people with Parkinson's disease (54% men; mean age 70