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A combined risk score enhances prediction of type 1 diabetes among susceptible children

Type 1 diabetes (T1D)-an autoimmune disease that destroys the pancreatic islets, resulting in insulin deficiency-often begins early in life when islet autoantibody appearance signals high risk1. However, clinical diabetes can follow in weeks or only after decades, and is very difficult to predict. Ketoacidosis at onset remains common2,3 and is most severe in the very young4,5, in whom it can be li

A Human Rights Qritique of European Judicial Review: Counter-terrorism Sanctions

Litigation involving individuals and entities whose financial assets have been frozen and whose names have been blacklisted in the fight against terrorism is on the rise around the world. However, the global ‘securitization’ of terrorism has rendered court performance of judicial review and the provision of remedies in these cases more difficult. What the main judicial challenges are, the need to

The Human Right to Science and the Regulation of Human Germline Engineering

There is currently no international consensus on how human germline engineering should be regulated. Existing national legislation fails to provide the governance framework necessary to regulate germline engineering in the CRISPR era. This is an obstacle to scientific and clinical advancements and inconsistent with human rights requirements. To move forward, we suggest that the human right to scie

Enforcing the Responsibility to Protect Through Solidarity Measures

Responsibility to Protect (R2P) provides a moral basis for collective action through the UN Security Council in reaction to mass atrocity situations. However, this avenue is not always available. The question then arises whether other actors can and should assume responsibility in such circumstances and, if so, which kinds of measures they may pursue. The present article examines this question wit

A Human Rights Appraisal of the Limits to Judicial Independence for International Criminal Justice

The UN Security Council's involvement in the area of international criminal justice raises concerns about judicial independence. Of primary concern in this study is the degree to which this political organ has come to determine and restrict jurisdiction of international criminal tribunals, with the effect of excluding cases involving alleged grave crimes by actors whose presence in situations of w

Searching for Common Ground on Universal Jurisdiction: The Clash between Formalism and Soft Law

The possibility of prosecuting serious international crimes before domestic foreign courts when territorial courts are unwilling and unable to perform this function and international criminal tribunals with suitable competences are unavailable has been intensively debated since the time of the Spanish arrest warrants against Pinochet. The African disapproval of decisions by European courts to exer

Phenomenology in multi-scalar extensions of the Standard Model

Denna sammanläggningsavhandling består av fyra artiklar, som alla berör olika utvidgningar av Standardmodellen (SM). De första två artiklarna behandlar en specifik, supersymmetrisk, storförenad teori (GUT), medan de senare två klassificerar alla anomali-fria instanser av 2-Higgs-dubblett modeller (2HDMs) med en gauge:ad abelsk symmetri. Artikel I. I denna artikel presenterar vi en alternativ lösniThis thesis is composed of four papers, which all treat various extensions to the Standard Model (SM). The first two papers concern a particular supersymmetric, grand-unified theory (GUT), while in the latter two, we classify anomaly-free implementations of two-Higgs doublet models (2HDM) with a gauged abelian symmetry. Paper I. In this paper, we present an alternative solution for avoiding GUT-sc