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Drought legacy affects microbial community trait distributions related to moisture along a savanna‐grassland precipitation gradient

Ecosystem models commonly use stable‐state assumptions to predict responses of soil microbial functions to environmental change. However, past climatic conditions can shape microbial functional responses resulting in a ‘legacy effect’. For instance, exposure to drier conditions in the field may shape how soil microbial communities respond to subsequent drought and drying and rewetting (DRW) event

A 10-bit Split-Capacitor SAR ADC with DAC Imbalance Estimation and Calibration

This paper presents a 10-bit SAR ADC with a sampling rate of 200 MS/s. To reduce area and power consumption, the ADC adopts a split-capacitor DAC, where the gain error is estimated and subsequently removed by means of a PRBS signal injected into the DAC and detected at the ADC output. The ADC has been designed and fabricated in a 22nm FD-SOI CMOS process, and achieves an SNDR of 48.7 dB and an SFD

A Design Method to Minimize the Impact of Bit Conversion Errors in SAR ADCs

This paper analyzes the bit conversion errors in high speed SAR ADCs and proposes a design method to minimize their impact on the ADC performance. By removing the SR latch from the output stage of the differential comparator, while using only one comparator output to generate the differential signals for the internal capacitive DAC, sparkle-code errors are avoided, and conversion errors from a pre

Barycentric Markov processes and stability of stochastic integrators

This thesis consists of four papers that broadly concerns two dierent topics. The rsttopic is so-called barycentric Markov processes. By a barycentric Markov process wemean a process that consists of a point/particle system evolving in (discrete) time,whose evolution depends in some way on the mean value of the current points in thesystem. In common for the three rst papers which are on this topicThis thesis consists of four papers that broadly concerns two dierent topics. The rsttopic is so-called barycentric Markov processes. By a barycentric Markov process wemean a process that consists of a point/particle system evolving in (discrete) time,whose evolution depends in some way on the mean value of the current points in thesystem. In common for the three rst papers which are on this topic

Public space as commodity : Social production of the Hong Kong waterfront

Although there has been a long tradition of public space-related land speculation and development, the recent success of the High Line in New York has highlighted the transformative effect carefully designed and curated public spaces can have on the local economy. By prioritising exchange value over use value, governments and developers are exploiting the production of public spaces as a means for

Circular Economy Policy at a Crossroads: Encouraging Durable Products or Enabling Faster Cycling of Short-lived Products?

Non-ownership models, where firms rather than consumers remain product owners, are advocated as a way for firms to prolong product lifetimes and contribute to a more Circular Economy. However, it has been suggested that such models could actually encourage ‘faster cycling’, meaning earlier product replacement and shorter product lifetimes. Within recent policy discussions, product durability to pr

The European Public Prosecutor: Quintessential Supranational Criminal Law?

This article critically examines the claim that EPPO is a proper federal supranational prosecutor. The article observes that the EPPO among policymakers and commentators appears to be a hallmark of the transformation of EU criminal law from an intergovernmental paradigm to a strong federal and supranational polity. The EPPO primarily stands out among other EU agencies by having been conferred with

Big Science, Ethics, and the Scalar Effects of Urban Planning

The urban expansion currently under development around the two materials science facilities MAX IV and European Spallation Source in Lund, Sweden, surrounds two meticulously designed research facilities steered by global demands. The new urban area, together with the research facilities dedicated to science and the development of knowledge, expands the city of Lund onto high-quality agricultural l

Associations of Plasma Phospho-Tau217 Levels with Tau Positron Emission Tomography in Early Alzheimer Disease

Importance: There is an urgent need for inexpensive and minimally invasive blood biomarkers for Alzheimer disease (AD) that could be used to detect early disease changes. Objective: To assess how early in the course of AD plasma levels of tau phosphorylated at threonine 217 (P-tau217) start to change compared with levels of established cerebrospinal fluid (CSF) and positron emission tomography (PE

Investigating the clinico-anatomical dissociation in the behavioral variant of Alzheimer disease

Background: We previously found temporoparietal-predominant atrophy patterns in the behavioral variant of Alzheimer’s disease (bvAD), with relative sparing of frontal regions. Here, we aimed to understand the clinico-anatomical dissociation in bvAD based on alternative neuroimaging markers. Methods: We retrospectively included 150 participants, including 29 bvAD, 28 “typical” amnestic-predominant

Internationella fredsbyrån och Nobels fredspris : Debatter i fredsfrågan på kongresser och i Nobeltal före 1914

In the 19th century, an extensive liberal and Christian international peace movement developed. In 1891, an umbrella organization, the International Peace Bureau (IPB), based in Bern, was formed to coordinate the international peace work that had previously been divided into a number of different national and international federations. This would prove successful. The establishment of a Nobel Priz

Genome-wide association analysis of type 2 diabetes in the EPIC-InterAct study

Type 2 diabetes (T2D) is a global public health challenge. Whilst the advent of genome-wide association studies has identified >400 genetic variants associated with T2D, our understanding of its biological mechanisms and translational insights is still limited. The EPIC-InterAct project, centred in 8 countries in the European Prospective Investigations into Cancer and Nutrition study, is one of th

Association is not prediction : A landscape of confused reporting in diabetes – A systematic review

Aims: Appropriate analysis of big data is fundamental to precision medicine. While statistical analyses often uncover numerous associations, associations themselves do not convey predictive value. Confusion between association and prediction harms clinicians, scientists, and ultimately, the patients. We analyzed published papers in the field of diabetes that refer to “prediction” in their titles.

Dependence of phase transitions on halide ratio in inorganic CsPb(Br: X I1- x )3perovskite thin films obtained from high-throughput experimentation

In this communication, we present the phase diagram of CsPb(BrxI1-x)3 (0 ≤ x ≤ 1, 300-585 K) obtained by high-throughput in situ GIWAXS measurements of a combinatorial thin film library. We find that all compositions convert to the cubic perovskite phase at high temperature and that the presence of bromide in the films stabilizes the metastable perovskite phases upon cool down. In accordance with

Dense sampling of bird diversity increases power of comparative genomics

Whole-genome sequencing projects are increasingly populating the tree of life and characterizing biodiversity1–4. Sparse taxon sampling has previously been proposed to confound phylogenetic inference5, and captures only a fraction of the genomic diversity. Here we report a substantial step towards the dense representation of avian phylogenetic and molecular diversity, by analysing 363 genomes from

Grain and dietary fiber intake and bladder cancer risk : a pooled analysis of prospective cohort studies

BACKGROUND: Higher intakes of whole grains and dietary fiber have been associated with lower risk of insulin resistance, hyperinsulinemia, and inflammation, which are known predisposing factors for cancer. OBJECTIVES: Because the evidence of association with bladder cancer (BC) is limited, we aimed to assess associations with BC risk for intakes of whole grains, refined grains, and dietary fiber.

Transport, destruction, and growth of pebbles in the gas envelope of a protoplanet

We analyze the size evolution of pebbles accreted into the gaseous envelope of a protoplanet growing in a protoplanetary disk, taking into account collisions driven by the relative sedimentation speed as well as the convective gas motion. Using a simple estimate of the convective gas speed based on the pebble accretion luminosity, we find that the speed of the convective gas is higher than the sed

Oumuamuas Passing through Molecular Clouds

The detections of 1I/‘Oumuamua and 2I/Borisov within just two years of each other impressively demonstrate that interstellar objects (ISOs) must be common in the Milky Way. Once released from their parent system, these ISOs travel for billions of years through interstellar space. While often imagined as empty, interstellar space contains gas and dust most prominent in the form of molecular clouds.

Association of amyloid-β CSF/PET discordance and tau load 5 years later

OBJECTIVE: To investigate the association between discordant β-amyloid (Aβ) PET and CSF biomarkers at baseline and the emergence of tau pathology 5 years later. METHODS: We included 730 Alzheimer's Disease Neuroimaging Initiative (ADNI) participants without dementia (282 cognitively normal, 448 mild cognitive impairment) with baseline [18F]florbetapir PET and CSF Aβ42 available. Aβ CSF/PET status