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Nazismen

En översiktlig analys av nazismens uppkomst och ideologi.

Resource mobilization andcontributing resources to acollective task by emergencyresponders: an experimental studyon collaboration in crisis response

Purpose: Twenty-first century crises reaffirm the need of faster mobilization of resources during crises. Without interorganizational collaboration and resource mobilization, organizing efficient response is not possible. Resource mobilization is an essential aspect of response. It ensures a faster and better response. Collaboration between teams of emergency responders may include commonly known

The “middle archive” : Exploring the practical and theoretical implications of a new concept in Sweden

The purpose of this paper is to study how the concept “middle archive” is related to the Swedish archival theory and practice, by exploring its background and its practical and theoretical implications. The overarching aim is to increase the understanding of the interrelations between the archival theory and practice, with a special focus on changes occurring in the digital environment in Sweden.

Alone on an island : The reassessment of an enigmatic species of Handmaiden Moth (Lepidoptera, Erebidae) endemic to Mauritius

Maculonaclia florida (de Joannis, 1906) has been one of the most mysterious moths of Mauritius, a small volcanic island located some 900 km east from Madagascar. Here, we reviewed its generic placement, phylogenetic relationships and the potential evolutionary scenarios leading to the current distribution of this unique Mauritian member of Syntomini. The species, known previously only from a few o

Contact allergy to fragrance mix I and its components in individuals with photocontact allergy to ketoprofen

BACKGROUND: Contact allergy to fragrance mix I (FM I) is over-represented in patients photoallergic to ketoprofen. The prevalence of contact allergy to two components of FM I, cinnamal and cinnamyl alcohol, in ketoprofen-photoallergic patients is higher than in dermatitis patients.OBJECTIVE: To explore the prevalence of contact allergy to FM I and its individual components in patients with photoco

Biological and small molecule strategies in migraine therapy with relation to the CGRP family of peptides

Migraine is one of the most common of neurological disorders with a global prevalence of up to 15%. One in five migraineurs have frequent episodic or chronic migraine requiring prophylactic treatment. In recent years, specific pharmaceutical treatments targeting calcitonin gene-related peptide (CGRP) signalling molecules have provided safe and effective treatments; monoclonal antibodies for prophy

PyPhase - A Python package for X-ray phase imaging

X-ray propagation-based imaging techniques are well established at synchrotron radiation and laboratory sources. However, most reconstruction algorithms for such image modalities, also known as phase-retrieval algorithms, have been developed specifically for one instrument by and for experts, making the development and diffusion of such techniques difficult. Here, PyPhase, a free and open-source p

Clinical efficacy of T-cell therapy after short-term BRAF-inhibitor priming in patients with checkpoint inhibitor-resistant metastatic melanoma

PURPOSE: Despite impressive response rates following adoptive transfer of autologous tumor-infiltrating lymphocytes (TILs) in patients with metastatic melanoma, improvement is needed to increase the efficacy and broaden the applicability of this treatment. We evaluated the use of vemurafenib, a small-molecule BRAF inhibitor with immunomodulatory properties, as priming before TIL harvest and adopti

Naturally acquired antibodies against Plasmodium falciparum : Friend or foe?

Antibodies are central to acquired immunity against malaria. Plasmodium falciparum elicits antibody responses against many of its protein components, but there is also formation of antibodies against different parts of the red blood cells, in which the parasites spend most of their time. In the absence of a decisive intervention such as a vaccine, people living in malaria endemic regions largely d

A relative approach to the validation of surrogate measures of safety

Surrogate measures of safety (SMoS) are meant to be an alternative/complement to crash data that enables a proactive approach to traffic safety. Validity is a fundamental property of SMoS that describes how well they reflect the quality of interest – traffic safety. However, typical validation studies are extremely resource demanding. Therefore, the aim of this study was to explore a relative appr

Quantification reveals early dynamics in Drosophila maternal gradients

The Bicoid (Bcd) protein is a primary determinant of early anterior-posterior (AP) axis specification in Drosophila embryogenesis. This morphogen is spatially distributed in an anterior-high gradient, and affects particular AP cell fates in a concentration-dependent manner. The early distribution and dynamics of the bicoid (bcd) mRNA, the source for the Bcd protein gradient, is not well understood

Modulating the bicoid gradient in space and time

Background: The formation of the Bicoid (Bcd) gradient in the early Drosophila is one of the most fascinating observations in biology and serves as a paradigm for gradient formation, yet its mechanism is still not fully understood. Two distinct models were proposed in the past, the SDD and the ARTS model.Results: We define novel cis- and trans-acting factors that are indispensable for gradient for

High-Resolution Proteomic Profiling Shows Sexual Dimorphism in Zebrafish Heart-Associated Proteins

Understanding the molecular basis of sexual dimorphism in the cardiovascular system may contribute to the improvement of the outcome in biological, pharmacological, and toxicological studies as well as on the development of sex-based drugs and therapeutic approaches. Label-free protein quantification using high-resolution mass spectrometry was applied to detect sex-based proteome differences in th

Fragmentation of relativistic nuclei in the α-particle model

We investigate reactions between high-energy oxygen and carbon nuclei and various nuclear targets. The beam nucleus is described by an α-particle model and the reaction products are classified into groups corresponding to inelastic collisions of one, two, three and four alpha particles. Excellent agreement with experiment is obtained.

Use of the drop volume of amniotic fluid in estimating the risk for respiratory distress syndrome in the newborn infant

The present study describes the testing and function of the drop-volume method in the analysis of fetal lung maturity with use of amniotic fluid. Elevated surface tension resulting from a lack of surface-active phospholipids (surfactant) is the primary etiologic defect in the development of respiratory distress syndrome. The drop-volume method quantifies the surface tension of amniotic fluid with

Effect of second-trimester sonographic cervical length on the risk of spontaneous preterm delivery in different risk groups : A prospective observational multicenter study

Introduction: The aim of the study is to compare the effect of cervical length measured with transvaginal ultrasound in the second trimester on the risk of spontaneous preterm delivery (PTD) between different risk groups of asymptomatic women with a singleton pregnancy. Material and methods: This is a pre-planned exploratory analysis of the CERVIX study, a prospective blinded multicenter diagnosti