Popular Abstract in Swedish Modellsystem för metall-DNA interaktioner Med fokus på anticanceraktiva platina(II) komplex Guld är ett mytomspunnet och fascinerande ämne som ger liv. Ett påstående som kanske förvånar, eftersom guld ofta förknippas med vackra smycken och rikedom. Att guld skulle ge liv var dock en förhoppning i Kina på 600-talet f. Kr. Där använde man nämligen metalliskt guld för medReactions of trans-dicyanodichloroaurate(III) trans-dibromodicyanoaurate(III), trans-diamminedichlorogold(III), cis-diammine(aqua)chloroplatinum(II), cis-ammineaqua-(cyclohexylamine)chloroplatinum(II), chloro(terpyridine)platinum(II) and chloro-(diethylenetriaminepalldium(II) with dimethyl sulfide, thionucleosides, thionucleotides and thione- and guanine-containing 17-mer oligonucleotides have bee

Popular Abstract in Swedish Stokastika effekter är av stor betydelse i många biofysiska system. Evolution, djurs sökande efter föda, spridning av virusinfektioner och stamcellsdifferentiering, är alla exempel på processer som på ett eller annat sätt är stokastiska till sin natur. Syftet med denna avhandling är att undersöka de verktyg som ofta används för att kvantifiera slumpmässighet i naturen oThe role of stochasticity throughout many biophysical systems is of great importance. From evolution to foraging, from the spreading of viruses to cell fate, all hinge in one way or another on inherent stochasticity. The aim of this thesis is to explore the tools often used to quantify randomness in nature, and employ these tools on a selected range of biophysical systems (Papers I-IV). In these p

Popular Abstract in Swedish I forskningsparker (Science Parks) finns ett antal resurser tillgängliga för de teknologibaserade företag (NTBF) som valt att lokalisera sig i dessa parker. Om företagen använder dessa resurser kan de också lättare bygga upp den resursbas som företag behöver för att kunna utvecklas och växa. I avhandlingen har tre kategorier av forskningsparksresurser identifierats: UniIn this thesis a strategy perspective (the resource-based view) is applied to the New Technology-Based Firms (NTBFs) in Science Parks, arguing that the Science Park provides the firms with a set of resources that if used could help them build their resource base and thus develop and grow. Three categories of resources are identified in the Science Park; University related resources, Science Park f

Teaching design history to future designers poses great challenges to me as an academic in the design field. There is a constant need to further describe and analyze how design and its history continuously are being made. The role of the designer implies the crafting of artefacts or at least an ability to communicate the possibility of them being materialized. Design history has mainly focused on

Since May 1998 Scandinavian group researchers and social psychologists have met bi-annually for what has to be called the GRASP conference. GRASP originally stood for ”Group as Paradox”. The first five conferences were held in Linköping, Lund, Stockholm and Skövde and, again, Linköping. The sixth conference was organized at Lund University May 15-16, 2008 under the auspices of the network Organi

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Popular Abstract in Swedish ?DNA-mikromatriser eller genchips? är idag väletablerade verktyg inom biologisk forskning och klinisk diagnostik. Genmikromatriser kan exempelvis användas för att i mikroskala studera genetiska skillnader mellan sjuka och friska vävnader. Informationen som då erhålls kan ge värdefulla upplysningar om sjukdomens natur och användas vid utveckling av nya läkemedel. GenernAntibody-based microarrays are among the novel class of rapidly evolving proteomic technologies. In recent years, antibody microarrays have emerged as a unique tool for high-throughput protein expression profiling with great promise within biomedicine and a wide range of potential applications, including disease diagnostics and biomarker discovery. In order to evolve the technology from small dedi

A strategy for feedback control of the glucose feed rate in cultivations of E.coli is discussed. By making probing pulses in the feedrate it is possible to detect and avoid undesirable by-productformation using a standard dissolved oxygen sensor. The feasibility of an improved and simplified probing algorithm is demonstrated by simulations as well as laboratory-scale experiments.

Redogörelse för ätten Cedercreutz uppkomst och koppling till ätten Tersmeden med särskild tonvikt på riksrådet Herman Cedercreutz, född Tersmeden.

Popular Abstract in English All living things somehow communicate with each other. Cell-to-cell communication, or signalling, occurs on the molecular level, regulating the body’s activities and coordinating various cell actions and is thereby valuable for realizing cell as well as system functions. Errors in the cellular transferred information may induce diseases such as cancer and autoimmune disGlypicans are multifunctional cell surface heparan sulphate proteoglycans co-regulating numerous signalling pathways, and are thereby involved in the control of cellular division, differentiation, and morphogenesis. The heparan sulphate (HS) chains are responsible for many of those biological functions; nevertheless recent studies suggest functional roles for the glypican core proteins in mediatin