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Defining and measuring ‘eczema control’ : an international qualitative study to explore the views of those living with and treating atopic eczema

Background: Atopic eczema (also known as eczema) is a chronic, inflammatory skin condition that often afflicts patients’ health and well-being. The Harmonising Outcome Measures for Eczema (HOME) initiative recommends that ‘long-term control of eczema’ is measured in all clinical trials 3 months or longer in duration. However, little has been published on what eczema control means to those living w

Are Central Bankers Inflation Nutters? An MCMC Estimator of the Long-Memory Parameter in a State Space Model

Inflation targeting is a common monetary policy regime. Inflation targets are often flexible in the sense that the central bank allows inflation to temporarily deviate from the target to avoid causing unnecessary volatility in the real economy. In this paper, we propose modeling the degree of flexibility using an autoregressive fractionally integrated moving average (ARFIMA) model. Assuming that tInflation targeting is a common monetary policy regime. Inflation targets are often flexible in the sense that the central bank allows inflation to temporarily deviate from the target to avoid causing unnecessary volatility in the real economy. In this paper, we propose modeling the degree of flexibility using an autoregressive fractionally integrated moving average (ARFIMA) model. Assuming that t

A Compilation of Serum Concentrations of 12 Antipsychotic Drugs in a Therapeutic Drug Monitoring Setting

BACKGROUND: No comprehensive collection of routine therapeutic drug monitoring data for antipsychotic drugs has been published. METHODS: In this compilation, data on 12 antipsychotics are presented. The drugs included are amisulpride (n = 506), aripiprazole (n = 1610), clozapine (n = 1189), flupentixol (n = 215), haloperidol (n = 390), olanzapine (n = 10,268), perphenazine (n = 1065), quetiapine (

Heterogeneity of Colorectal Cancer Risk Factors by Anatomical Subsite in 10 European Countries: A Multinational Cohort Study

Background & Aims: Colorectal cancer located at different anatomical subsites may have distinct etiologies and risk factors. Previous studies that have examined this hypothesis have yielded inconsistent results, possibly because most studies have been of insufficient size to identify heterogeneous associations with precision. Methods: In the European Prospective Investigation into Cancer and N

Lokal arbetsmarknadspolitik med fokus på autonomi och delaktighet : Ett brukarperspektiv på Det stegvisa jobb- och kunskapslyftet

Inledning När det gäller arbetsmarknadspolitik på det kommunala planet, har det ofta funnits utrymme för profession och politik att skapa och utforma lokala program. Utgångspunkterna har inte sällan varit ’innovativa idéer’ i syfte att tillgodose flera behov samtidigt. Sällan har verksamheterna vilat på forskning och beprövad erfarenhet. Systematisk uppföljning och kunskap om programmens konsekven

In-vivo validation of interpolation-based phase offset correction in cardiovascular magnetic resonance flow quantification : A multi-vendor, multi-center study

Background: A velocity offset error in phase contrast cardiovascular magnetic resonance (CMR) imaging is a known problem in clinical assessment of flow volumes in vessels around the heart. Earlier studies have shown that this offset error is clinically relevant over different systems, and cannot be removed by protocol optimization. Correction methods using phantom measurements are time consuming,

Currency Unions

A currency union is when several independent sovereign nations share a common currency. This has been a recurring phenomenon in monetary history. In this article I study the theoretical foundations of such unions, and discuss some important currency unions in history, most notably the case of the US. Finally I contrast the design of the EMU with economic theories and historical experiences of curr

Biomarkers of blood cadmium and incidence of cardiovascular events in non-smokers : Results from a population-based proteomics study

Background: Cadmium is a toxic metal with multiple adverse health effects, including risk of cardiovascular disease (CVD). The mechanistic link between cadmium and CVD is unclear. Our aim was to examine the associations between blood cadmium (B-Cd) and 88 potential protein biomarkers of CVD. Methods: B-Cd and 88 plasma proteins were measured in a community-based prospective cohort, the Malmö Diet

Team climate inventory with a merged organization

The present study examines the team climate for innovation in work teams within a newly merged organization. Four teams working at a regional head office of a Social Insurance organization answered the Team Climate Inventory. The results were compared to those of a study by Agrell and Gustafson of more stable teams. The compareson showed that parti¬cipative safety and support for innovation were r

The major histocompatibility complex (MHC) of the secondary transplant tissue donor influences the cross-reactivity of alloreactive memory cells.

Memory cells are currently thought to be a major barrier to tolerance induction in transplantation. However, whether alloreactive memory cells resulting from a primary transplant have cross-reactivity in a second transplant is unclear. Here, we used skin transplantation from BALB/c mice donors to pre-sensitize C(57) BL/6 (B6) mice. One month later, several strains of mice (including BALB/c, DBA/2,

A Home-Proxy Based Wireless Internet Framework in Supporting Mobility and Roaming of Real-Time Services

Due to the lack of support in mobility and quality of service, today's IF-based networks have some inherent limitations: for delivering multimedia services in a mobile environment. In the past few years, these issues have been addressed in the research community and the resulting techniques: are being standardised. However, these development have been done in isolation and become incompatible with