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Segmentation of echocardiographic image sequences using spatio-temporal information

This paper describes a new method for improving border detection in image sequences by including both spatial and temporal information. The method is based on three dimensional quadrature filters for estimating local orientation. A simplification that gives a significant reduction in computational demand is also presented. The border detection framework is combined with a segmentation algorithm ba

Tensor field visualisation using adaptive filtering of noise fields combined with glyph rendering

While many methods exist for visualising scalar and vector data, visualisation of tensor data is still troublesome. We present a method for visualising second order tensors in three dimensions using a hybrid between direct volume rendering and glyph rendering. An overview scalar field is created by using three-dimensional adaptive filtering of a scalar field containing noise. The filtering process

Mesoporous silica as a matrix for photocatalytic titanium dioxide nanoparticles : lipid membrane interactions

In the present study, we investigate the combined interaction of mesoporous silica (SiO2) and photocatalytic titanium dioxide (TiO2) nanoparticles with lipid membranes, using neutron reflectometry (NR), cryo-transmission electron microscopy (cryo-TEM), fluorescence oxidation assays, dynamic light scattering (DLS), and ζ-potential measurements. Based on DLS, TiO2 nanoparticles were found to display

Fluid flow and heat transfer in a rectangular ribbed channel with a hierarchical design for turbine blade internal cooling

For internal cooling of a turbine blade, various advanced rib turbulators can markedly contribute to the heat transfer enhancement while suffering a great increase in pressure loss. In those designs, ribs with the same configuration are periodically and evenly mounted on the channel wall. In this context, this work proposes a hierarchical design concept to optimize the rib arrangement with the des

Big Science and Research Infrastructures in Europe : Conclusions and outlook

Big Science and Research Infrastructures are ostensibly important features of contemporary European science and innovation policy. But while we can look back on half a century of attention to Big Science, in political debate as well as scholarly studies of depth and breadth, Research Infrastructures is a more recent phenomenon. In this concluding chapter, we summarize the findings and the contribu

SHG Imaging for Tissue Engineering Applications

Treatment of lost tissue oen relies on transplantations, either of donor or of autologous tissue. Both alternatives have limitations; there is for example a limited supply of donor transplants, which also require immunosuppression therapy with possible side eects. Transplanted autologous tissue may lack some of the functions of the original tissue and the procedure may also introduce complications

Navigating Human Rights, Feminism, and History : Egyptian Feminist Activists’ Demands for Constitutional Equality, 2012–2014

This article analyzes the efforts of Egyptian feminist activists to insert gender equality in the country’s post-revolutionary constitutions in 2012 and 2014. While the literature on women’s political role during this period provides insights into exclusionary gender practices and conditions for bargaining power structures, this study contributes with a conceptual analysis of how feminist activist

Structural basis of activation and antagonism of receptor signaling mediated by interleukin-27

Interleukin-27 (IL-27) uniquely assembles p28 and EBI3 subunits to a heterodimeric cytokine that signals via IL-27Rα and gp130. To provide the structural framework for receptor activation by IL-27 and its emerging therapeutic targeting, we report here crystal structures of mouse IL-27 in complex with IL-27Rα and of human IL-27 in complex with SRF388, a monoclonal antibody undergoing clinical trial

Dynamical Modeling of Cloud Applications for Runtime Performance Management

Cloud computing has quickly grown to become an essential component in many modern-day software applications. It allows consumers, such as a provider of some web service, to quickly and on demand obtain the necessary computational resources to run their applications. It is desirable for these service providers to keep the running cost of their cloud application low while adhering to various perform

Spatial variations in financial constraints of SMEs—evidence from firm-level estimates of investment-cash flow sensitivities in Sweden

It is well established that there is uneven availability of credit across space, in particular for SMEs. The evidence on whether this translates into differences in actual business investments remains scarce. We assess this question by using firm-level data for Swedish firms and estimate the extent to which the average investment-cash flow sensitivities of firms vary across the urban–rural hierarc

Elevated plasma WIF-1 levels are associated with worse prognosis in heart failure with pulmonary hypertension

Aims: Heart failure (HF) is a progressive condition that is becoming more prevalent in the ageing population. Pulmonary hypertension is a common complicating factor in HF and negatively impacts survival. Plasma biomarkers are a potential method for determining the prognosis of patients with left heart failure with pulmonary hypertension (LHF-PH). We aimed to analyse the prognostic capability of 33

The EU’s role in fighting global imbalances

The EU’s Role in Fighting Global Imbalances looks at the role of the European Union in addressing some of the greatest challenges of our time: poverty, protectionism, climate change, and human trafficking. Contributions from ten leading scholars in the fields of economics, law, and political science provide in-depth analyses of three key dimensions of EU foreign policy, namely: the internal challe

Role of Neuroinflammation in Parkinson's Disease and Related Disorders

Synucleinopathies are neurodegenerative disorders characterized by intracellular protein aggregates, progressive neurodegeneration, and neuroinflammation. Alpha-synuclein (a-syn) is the principal component of intracellular aggregates and can be modified by several mutations and post-translational modifications (PTMs), which can alter the protein structure affecting its aggregation, toxicity, and a

Nondestructive Testing Using mm-Wave Sparse Imaging Verified for Singly Curved Composite Panels

Nondestructive testing of composite materials is important in aerospace applications, and mm-wave imaging has been increasingly used for this purpose. Imaging is traditionally performed using Fourier methods, with inverse methods being an alternative. This communication presents a mm-wave imaging method with an inverse approach intended for nondestructive testing of singly curved composite panels

Predicting Grade group 2 or higher cancer at prostate biopsy by 4Kscore in blood and uCaP microRNA model in urine

Elevated prostate-specific antigen (PSA) levels often lead to unnecessary and possibly harmful transrectal ultrasound guided biopsy, e.g. when the biopsy is negative or contains only low-grade insignificant cancer, unlikely to become symptomatic in the man’s normal lifespan. A model based on four-kallikrein markers in blood (commercialized as 4Kscore) predicts risk of Grade group 2 or higher prost

Testing the migration syndrome : Comparative fecundity of migratory and non-migratory nymphaline butterflies

Empirical studies have shown a positive relationship between migration and fecundity, suggesting a ‘migration syndrome’ that also includes delayed reproduction and an extended reproductive lifespan. At the same time, life history theory predicts that the cost of migration should result in lower fecundity because both traits draw from a common resource. We test whether migration is associated with