Sökresultat

Filtyp

Din sökning på "*" gav 536997 sökträffar

Predicting Turns in Proteins with a Unified Model

Motivation: Turns are a critical element of the structure of a protein; turns play a crucial role in loops, folds, and interactions. Current prediction methods are well developed for the prediction of individual turn types, including α-turn, β-turn, and γ-turn, etc. However, for further protein structure and function prediction it is necessary to develop a uniform model that can accurately predict

DomHR : Accurately Identifying Domain Boundaries in Proteins Using a Hinge Region Strategy

Motivation: The precise prediction of protein domains, which are the structural, functional and evolutionary units of proteins, has been a research focus in recent years. Although many methods have been presented for predicting protein domains and boundaries, the accuracy of predictions could be improved. Results: In this study we present a novel approach, DomHR, which is an accurate predictor of

Response to dietary l-glutamine supplementation in weaned piglets : A serum metabolomic comparison and hepatic metabolic regulation analysis

A novel metabolomic method based on gas chromatography-mass spectrometry was applied to investigate serum metabolites in response to dietary Gln supplementation in piglets. Sixteen, 21-d-old pigs were weaned and assigned randomly to 2 isonitrogenous diets: 1) Gln diet, which contained 1% L-Gln (as-fed basis), and 2) control diet, which contained LAla to make this diet isonitrogenous with the Gln d

The feasibility of climate action : Bridging the inside and the outside view through feasibility spaces

The feasibility of different options to reduce the risks of climate change has engaged scholars for decades. Yet there is no agreement on how to define and assess feasibility. We define feasible as “do-able under realistic assumptions.” A sound feasibility assessment is based on causal reasoning; enables comparison of feasibility across climate options, contexts, and implementation levels; and ref

One plan, multiple models: The General Plan for Stockholm as an instaurational text.

The 1952 General Plan for Stockholm is often seen as Sweden’s most important postwar planning document, sketching the outlines of the social-democratic urban region. In the words of city planning director Sven Markelius, it showcased ”the possibilities for building a townscape, or a milieu, with all its components that satisfy the demands we have on urban life today”. This plan has since acquired The 1952 General Plan for Stockholm is often seen as Sweden’s most important postwar planning document, sketching the outlines of the social-democratic urban region. In the words of city planning director Sven Markelius, it showcased ”the possibilities for building a townscape, or a milieu, with all its components that satisfy the demands we have on urban life today”. This plan has since acquired

Rectal washout in rectal cancer surgery

BackgroundRectal washout (RW) is performed to eliminate intraluminal cancer cells and thereby reducing the risk of local recurrence (LR). The overall aim of this thesis was to investigate the importance of RW in rectal cancer surgery.MethodPaper I: Survey of the current practice of RW among Swedish colorectal units.Paper II: The association between RW and 30-day postoperative complications after a

Parental Leave Reforms in South Korea, 1995–2021: Policy Translation and Institutional Legacies

This article aims to explore how policy translation and institutional legacies have shaped South Korean parental leave policies between 1995 and 2021. It draws on a document analysis of central political documents and interviews with a number of key policy actors in South Korea. The findings show that reforms of parental leave policies were implemented according to four major rationales: maternityThis article aims to explore how policy translation and institutional legacies have shaped South Korean parental leave policies between 1995 and 2021. It draws on a document analysis of central political documents and interviews with a number of key policy actors in South Korea. The findings show that reforms of parental leave policies were implemented according to four major rationales: maternity

Alcohol and aging: a multimethod study on heterogeneity and multidimensionality

Background and Objectives: With an ageing population, the number of older persons with substance use problems, particularly problematic alcohol use, is increasing. Despite grow­ing recognition of the negative consequences of problematic alcohol use on older persons, there is a dearth of knowledge about the alcohol use profiles and the dimensionality of alcohol problems in older people. Moreover, l

Random-Access Neural Compression of Material Textures

The continuous advancement of photorealism in rendering is accompaniedby a growth in texture data and, consequently, increasing storage and memory demands. To address this issue, we propose a novel neural compressiontechnique specifically designed for material textures. We unlock two morelevels of detail, i.e., 16× more texels, using low bitrate compression, withimage quality that is better than a

Luminance-Preserving and Temporally Stable Daltonization

We propose a novel, real-time algorithm for recoloring images to improve the experience for a color vision deficient observer. The output is temporally stable and preserves luminance, the most important visual cue. It runs in 0.2 ms per frame on a GPU.

Occupational risk of COVID-19 in foreign-born employees in Denmark

BACKGROUND: Foreign-born workers in high-income countries experience higher rates of COVID-19 but the causes are only partially known.AIMS: To examine if the occupational risk of COVID-19 in foreign-born workers deviates from the risk in native-born employees in Denmark.METHODS: Within a registry-based cohort of all residents employed in Denmark (n = 2 451 542), we identified four-digit DISCO-08 o

Building Stronger Bridges: Strategies for Improving Communication and Collaboration Between Industry and Academia in Software Engineering

Background: The software engineering community has expressed growing concern regarding the need for more connections between research and practice. Despite the large amount of knowledge researchers generate, its impact on real-world practice is uncertain. Meanwhile, practitioners in industry often struggle to access and utilize relevant research outcomes that could inform and enhance their work. C

Engaging the missing actor : lessons learned from an age-management intervention targeting line managers and their HR partners

Purpose – This study aims to describe and evaluate the impact of a participatory age-management intervention on the knowledge, awareness and engagement of line managers and their HR partners from six health-care organizations in Sweden.Design/methodology/approach – The learning workshops consisted of lectures, discussions, feedback and exchange of experiences with colleagues and invited experts. A

The dynamic floor of Yellowstone Lake, Wyoming, USA : The last 14 k.y. of hydrothermal explosions, venting, doming, and faulting

Hydrothermal explosions are significant potential hazards in Yellowstone National Park, Wyoming, USA. The northern Yellowstone Lake area hosts the three largest hydrothermal explosion craters known on Earth empowered by the highest heat flow values in Yellowstone and active seismicity and deformation. Geological and geochemical studies of eighteen sublacustrine cores provide the first detailed syn

Microstructure in SOFC: electrochemical simulations and experiments

Solid oxide fuel cells (SOFCs) are highly efficient and environmentally friendly power sources that convert chemical energy directly into electricity and heat, without the need for combustion. Despite their many benefits, the performance and durability of SOFCs heavily depend on the quality of their porous anode and cathode components. There are significant challenges with regard to their commerci

On the Challenges of Software Performance Optimization with Statistical Methods

Most recent programming languages, such as Java, Python and Ruby, include a collection framework as part of their standard library (or runtime). The Java Collection Framework provides a number of collection classes, some of which implement the same abstract data type, making them interchangeable. Developers can therefore choose between several functionally equivalent options. Since collections hav

A practical approach to curate clonal hematopoiesis of indeterminate potential in human genetic data sets

Clonal hematopoiesis of indeterminate potential (CHIP) is a common form of age-related somatic mosaicism that is associated with significant morbidity and mortality. CHIP mutations can be identified in peripheral blood samples that are sequenced using approaches that cover the whole genome, the whole exome, or targeted genetic regions; however, differentiating true CHIP mutations from sequencing a

Antenna System Design for 5G and Beyond – A Modal Approach

Antennas are one of the key components that empower a new generation of wireless technologies, such as 5G and new radar systems. It has been shown that antenna design strategies based on modal theories represent a powerful systematic approach to design practical antenna systems with high performance. In this thesis, several innovative multi-antenna systems are proposed for wireless applications in