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Discriminatory analysis of biochip-derived protein patterns in CSF and plasma in neurodegenerative diseases

The role of biomarkers in neurodegenerative diseases has been emphasized by recent research. Future clinical demands for identifying diseases at an early stage may render them essential. The aim of this pilot study was to test the analytical performance of two multiplex assays of cerebral markers on a well-defined clinical material consisting of patients with various neurodegenerative diseases. We

Detecting Stochastic Nuclear Quadrupole Resonance Signals in the Presence of Strong Radio Frequency Interference

Nuclear quadrupole resonance (NQR) is a radio frequency (RF) spectroscopic technique, allowing the detection of many high explosives and narcotics. In practice, NQR is restricted by the low signal-to-noise ratio of the observed signals, a problem further exacerbated by the presence of strong RF interference (RFI). The current literature focuses on the use of conventional, multiple-pulsed NQR (cNQR

Fast antenna selection algorithms for MIMO systems

We consider the capacity of multiple-input-multiple-output (MIMO) systems with reduced complexity. One link end uses all available antennas, while the other chooses the "best" L out of N antennas. The selection of the optimum antenna subset requires an exhaustive search of all possible combinations, involving (/sub L//sup N/) computations of determinants of size L /spl times/ L, which can become p

Det hotade grevskapet : Per Brahe den yngres minnesmärken

The threatened estate - the memorials of Per Brahe junior On the background of the present research on memorials and monuments follows a study of a number of memorials erected by the count Per Brahe junior between 1653 and 1680 on Visingsö and in Skärstad in Småland, at Dimbo in Västergötland and Östra Ryd in Uppland. The memorials belong to a period, when his county Visingsborg in Sweden and baro

Implementation and certification of environmental management systems in small enterprises: Approches and limitations

Many small enterprises that are planning to implement environmental management systems (EMSs) and get certified according to the ISO 14001 standard or EMAS regulation have experienced a lot of barriers on the road towards certification. The standards are perceived as bureaucratic and represent a way of working that often fits poorly into the organizational culture and decision-making structure of

Tripeptide Interference with Human Immunodeficiency Virus Type 1 Morphogenesis

Capsid assembly during virus replication is a potential target for antiviral therapy. The Gag polyprotein is the main structural component of retroviral particles, and in human immunodeficiency virus type 1 (HIV-1), it contains the sequences for the matrix, capsid, nucleocapsid, and several small polypeptides. Here, we report that at a concentration of 100 M, 7 of 83 tripeptide amides from the car

Hypogonadism in young men treated for cancer.

An ever-increasing proportion of young males treated for cancer are cured. Therefore, one of the major challenges of modern Clinical Oncology is to ensure good quality of life. Cancer disease per se as well as cancer treatment may have a negative impact on androgen production, thereby leading to subclinical or clinically overt hypogonadism. Since the symptoms of androgen deficiency are rather unsp

Assistive devices for people affected by leprosy: underutilised facilitators of functioning?

OBJECTIVES: People affected by leprosy and their families face social and economic problems. The focus of interventions is often on prevention of disabilities and socioeconomic rehabilitation. The objective of this study was to explore to what extent the potential of assistive devices to facilitate activities and participation of people affected by leprosy has been utilised. DESIGN: Published lite