Introduction: Reverse transcriptase quantitative PCR (RT-qPCR) is considered the method of choice for measurable residual disease (MRD) assessment in NPM1-mutated acute myeloid leukemia (AML). MRD can also be determined with DNA-based methods offering certain advantages. We here compared the DNA-based methods quantitative PCR (qPCR), droplet digital PCR (ddPCR), and targeted deep sequencing (deep

Artikel om vitabussaktionen varigenom mellan 15 000 och 30 000 fångar från koncentrationsläger i Nazityskland kom till Sverige.

Restrictions in empirical research of biological communities have limited our understanding of the combined influence of environmental variability and system structure on community composition. Spatial patterns of community composition in less accessible systems, such as marine benthos, can often not be explained by many factors beyond the direct impact of the environment on community members. We

A co-designed (3+3)-port antenna for dual-band operation that requires no feeding or decoupling network is proposed and verified. The antenna consists of six ports which are divided into two groups that resonate in two differentfrequency ranges. The basic radiating element is a tri-modal patch in a folded snowflake-shaped structure with the largest antenna dimension of 0.48λ1 or 0.68λ2, where λ1 and

Bronchiolitis obliterans syndrome (BOS), a common form of chronic lung allograft dysfunction, is the major limitation to long-term survival after lung transplantation. The histological correlate is progressive, fibrotic occlusion of small airways, obliterative bronchiolitis lesions, ultimately leading to organ failure. The molecular composition of these lesions is unknown. By laser-capture microdi

Beliefs about the moral status of children have changed significantly in recent decades in the Western world. At the same time, knowledge about likely consequences for children of individual, parental, and societal choices has grown, as has the array of choices that (prospective) parents may have at their disposal. The intersection between these beliefs, this new knowledge, and these new choices h

OBJECTIVE: The objective was to examine the association between primary care consultations and a Care Need Index (CNI) used to compensate Swedish primary care practices for the extra workload associated with patients with low socioeconomic status.DESIGN: Observational study combining graphical analysis with linear regressions of cross-sectional administrative practice-level data.SETTING: Three Swe

The emergence of markets for online physician consultations -- direct-to-consumers telemedicine (DCT) -- is transforming healthcare services in many nations. The convenience of DCT lowers the cost of seeking care, thus potentially increasing demand. Yet, it is not known whether patients consuming online care turn to traditional providers as well. This is one of the first studies to causally assess

Leaf area index (LAI) is a key ecological indicator for describing the structure of canopies and for modelling energy exchange between atmosphere and biosphere. While LAI of the forest overstory can be accurately assessed over large spatial scales via remote sensing, LAI of the forest understory (LAIu) is still largely ignored in ecological studies and ecosystem modelling due to the fact that it i

Vem bygger vi för? är den övergripande frågan i denna licentiatuppsats. Uppsatsensyftar till att belysa och problematisera hur människor inkluderas eller exkluderas iden byggda miljön, till följd av om, och hur mänsklig mångfald ges uttryck ochplats i plan och byggprocessen. Den bygger på två delstudier som behandlar hur detänkta användarna av den byggda miljön kategoriseras i planhandlingar ochstWho are we building for? This is the overarching question in this licentiate thesis.The thesis aims to shed light on and problematise how people are included orexcluded in the built environment due to if, and how human diversity is expressedand visible in the plan and construction process. It is based on two studies that dealwith how the intended users of the built environment are categorised in p

Peptides and proteins have evolved to self-assemble into supramolecular entities through a set of non-covalent interactions. Such structures and materials provide the functional basis of life. Crucially, biomolecular assembly processes can be highly sensitive to and modulated by environmental conditions, including temperature, light, ionic strength and pH, providing the inspiration for the develop

Fluctuations of neuronal activities in the brain may underlie relatively slow components of neurofunctional alterations, which can be modulated by food intake and related systemic metabolic statuses. Glutamatergic neurotransmission plays a major role in the regulation of excitatory tones in the central nervous system, although just how dietary elements contribute to the tuning of this system remai